Literature DB >> 22204997

ED identification of patients with severe sepsis/septic shock decreases mortality in a community hospital.

Aveh Bastani1, Stephen Galens, Albert Rocchini, Rosemarie Walch, Blerina Shaqiri, Kristen Palomba, Anne Marie Milewski, Angela Falzarano, Denise Loch, William Anderson.   

Abstract

STUDY
OBJECTIVES: Our objective was to quantify the mortality difference between patients with severe sepsis/septic shock (SS/SS) identified in the emergency department (EDI) vs those not identified in the emergency department (NEDI) within our community hospital.
METHODS: We conducted a retrospective review of all patients with SS/SS from July 2007 to January 2010 who were admitted to the intensive care unit within our community hospital. Our primary outcome measure was the difference in mortality rates of patients with SS/SS between the EDI and NEDI cohorts. Our secondary outcome measures included the final disposition, the length of stay, and direct cost (DC) for both groups. The data were analyzed using a 2 × 2 contingency table and the Fisher exact test for significance to compare the mortality rates between groups. Lengths of stay and DC between both groups were reported as medians, and significance was calculated using the Mann-Whitney U test.
RESULTS: A total of 267 patients with SS/SS were identified during the 31-month study period. Of these patients, 155 were EDI patients with a mortality rate of 27.7%, and 112 were NEDI patients with a mortality rate of 41.1%. This represents an absolute difference in mortality rates of 13.4% between the 2 groups (P = .0257). The median length of stay between both groups was 7 days for the EDI group and 12.5 days for the NEDI group, translating to median DCs of $9861.01 vs $16 031.07.
CONCLUSIONS: Emergency department identification of patients with SS/SS in the community hospital significantly improves mortality.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 22204997     DOI: 10.1016/j.ajem.2011.09.029

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  4 in total

Review 1.  Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Authors:  Manu Shankar-Hari; Gary S Phillips; Mitchell L Levy; Christopher W Seymour; Vincent X Liu; Clifford S Deutschman; Derek C Angus; Gordon D Rubenfeld; Mervyn Singer
Journal:  JAMA       Date:  2016-02-23       Impact factor: 56.272

2.  Delayed antimicrobial therapy increases mortality and organ dysfunction duration in pediatric sepsis.

Authors:  Scott L Weiss; Julie C Fitzgerald; Fran Balamuth; Elizabeth R Alpern; Jane Lavelle; Marianne Chilutti; Robert Grundmeier; Vinay M Nadkarni; Neal J Thomas
Journal:  Crit Care Med       Date:  2014-11       Impact factor: 7.598

3.  Comparison of diagnostic and prognostic utility of lactate and procalcitonin for sepsis in adult cancer patients presenting to emergency department with systemic inflammatory response syndrome.

Authors:  Esra Keçe; Elif Yaka; Serkan Yılmaz; Nurettin Özgür Doğan; Cansu Alyeşil; Murat Pekdemir
Journal:  Turk J Emerg Med       Date:  2016-03-10

4.  Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department.

Authors:  Adam Linder; Ryan Arnold; John H Boyd; Marko Zindovic; Igor Zindovic; Anna Lange; Magnus Paulsson; Patrik Nyberg; James A Russell; David Pritchard; Bertil Christensson; Per Åkesson
Journal:  Crit Care Med       Date:  2015-11       Impact factor: 7.598

  4 in total

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