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Literature DB >> 22202094

Modulation of cell cycle regulators by HDACs.

Abstract

Histone deacetylases (HDACs) catalyze the deacetylation of lysine residues on histones and non-histone proteins. HDACs have been shown to control the functions of key cell cycle proteins. Consistent with this, the overexpression of HDACs has been observed in multiple cancers, resulting in deregulation of the cell cycle and uncontrolled proliferation. This review focuses on the impact that HDACs have on cell cycle control through the deacetylation of proteins.

Entities: Chemical

Mesh：

Substances：

Year: 2012 PMID： 22202094 PMCID： PMC3990255 DOI： 10.2741/s303

Source DB: PubMed Journal: Front Biosci (Schol Ed) ISSN： 1945-0516

83 in total

1. Inhibitors of histone deacetylase are potentially effective anticancer agents.

Authors: P A Marks; R A Rifkind; V M Richon; R Breslow
Journal: Clin Cancer Res Date: 2001-04 Impact factor: 12.531

2. E2F family members are differentially regulated by reversible acetylation.

Authors: G Marzio; C Wagener; M I Gutierrez; P Cartwright; K Helin; M Giacca
Journal: J Biol Chem Date: 2000-04-14 Impact factor: 5.157

3. Retinoblastoma protein represses transcription by recruiting a histone deacetylase.

Authors: L Magnaghi-Jaulin; R Groisman; I Naguibneva; P Robin; S Lorain; J P Le Villain; F Troalen; D Trouche; A Harel-Bellan
Journal: Nature Date: 1998-02-05 Impact factor: 49.962

Review 4. The clinical development of histone deacetylase inhibitors as targeted anticancer drugs.

Authors: Paul A Marks
Journal: Expert Opin Investig Drugs Date: 2010-09 Impact factor: 6.206

5. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes.

Authors: J DeGregori; T Kowalik; J R Nevins
Journal: Mol Cell Biol Date: 1995-08 Impact factor: 4.272

6. Histone deacetylase 1 can repress transcription by binding to Sp1.

Authors: A Doetzlhofer; H Rotheneder; G Lagger; M Koranda; V Kurtev; G Brosch; E Wintersberger; C Seiser
Journal: Mol Cell Biol Date: 1999-08 Impact factor: 4.272

7. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

Authors: Gerda Lagger; Angelika Doetzlhofer; Bernd Schuettengruber; Eva Haidweger; Elisabeth Simboeck; Julia Tischler; Susanna Chiocca; Guntram Suske; Hans Rotheneder; Erhard Wintersberger; Christian Seiser
Journal: Mol Cell Biol Date: 2003-04 Impact factor: 4.272

8. Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification.

Authors: Snezana Milutinovic; Qianli Zhuang; Moshe Szyf
Journal: J Biol Chem Date: 2002-04-02 Impact factor: 5.157

9. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3.

Authors: D E Ayer; Q A Lawrence; R N Eisenman
Journal: Cell Date: 1995-03-10 Impact factor: 41.582

10. Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin.

Authors: Andriana Margariti; Anna Zampetaki; Qingzhong Xiao; Boda Zhou; Eirini Karamariti; Daniel Martin; Xiaoke Yin; Manuel Mayr; Hongling Li; Zhongyi Zhang; Elena De Falco; Yanhua Hu; Gillian Cockerill; Qingbo Xu; Lingfang Zeng
Journal: Circ Res Date: 2010-03-11 Impact factor: 17.367

17 in total

1. Compression regulates gene expression of chondrocytes through HDAC4 nuclear relocation via PP2A-dependent HDAC4 dephosphorylation.

Authors: Chongwei Chen; Xiaochun Wei; Shaowei Wang; Qiang Jiao; Yang Zhang; Guoqing Du; Xiaohu Wang; Fangyuan Wei; Jianzhong Zhang; Lei Wei
Journal: Biochim Biophys Acta Date: 2016-04-19

2. Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.

Authors: Yemin Wang; Shary Yuting Chen; Shane Colborne; Galen Lambert; Chae Young Shin; Nancy Dos Santos; Krystal A Orlando; Jessica D Lang; William P D Hendricks; Marcel B Bally; Anthony N Karnezis; Ralf Hass; T Michael Underhill; Gregg B Morin; Jeffrey M Trent; Bernard E Weissman; David G Huntsman
Journal: Mol Cancer Ther Date: 2018-09-19 Impact factor: 6.261

3. High HDAC5 expression correlates with a poor prognosis and the tumor immune microenvironment in gastric cancer.

Authors: Li Yuan; Can Hu; Pengcheng Yu; Zhehan Bao; Yuhang Xia; Bo Zhang; Yi Wang
Journal: Ann Transl Med Date: 2022-09

4. Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplification.

Authors: N Sanjib Banerjee; Dianne W Moore; Thomas R Broker; Louise T Chow
Journal: Proc Natl Acad Sci U S A Date: 2018-11-01 Impact factor: 11.205

5. An Acyl-CoA N-Acyltransferase Regulates Meristem Phase Change and Plant Architecture in Barley.

Authors: Agatha Walla; G Wilma van Esse; Gwendolyn K Kirschner; Ganggang Guo; Annika Brünje; Iris Finkemeier; Rüdiger Simon; Maria von Korff
Journal: Plant Physiol Date: 2020-05-06 Impact factor: 8.340

6. Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells.

Authors: Sofia R Gameiro; Anthony S Malamas; Kwong Y Tsang; Soldano Ferrone; James W Hodge
Journal: Oncotarget Date: 2016-02-16