| Literature DB >> 22200928 |
Changbei Ma1, Edward S Yeung, Shengda Qi, Rui Han.
Abstract
We have developed a new methodology for miRNA assay using chemiluminescence imaging by poly(U) polymerase catalyzed miRNA polymerization. This method is very sensitive with a 50 fM limit of detection, which is comparable to or better than current assay methods. Multiplex detection for miRNA can be easily realized by introducing different capture probes onto the biosensor array, which will make it highly versatile for various research purposes.Mesh:
Substances:
Year: 2011 PMID: 22200928 DOI: 10.1007/s00216-011-5653-4
Source DB: PubMed Journal: Anal Bioanal Chem ISSN: 1618-2642 Impact factor: 4.142