| Literature DB >> 22200607 |
Meghan C Drummond1, Inna A Belyantseva, Karen H Friderici, Thomas B Friedman.
Abstract
Hereditary deafness is genetically heterogeneous such that mutations of many different genes can cause hearing loss. This review focuses on the evidence and implications that several of these deafness genes encode actin-interacting proteins or actin itself. There is a growing appreciation of the contribution of the actin interactome in stereocilia development, maintenance, mechanotransduction and malfunction of the auditory system. Published by Elsevier B.V.Entities:
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Year: 2011 PMID： 22200607 PMCID： PMC3403717 DOI： 10.1016/j.heares.2011.12.003
Source DB: PubMed Journal: Hear Res ISSN： 0378-5955 Impact factor: 3.208