Literature DB >> 22197996

Is the spinal motion segment a diarthrodial polyaxial joint: what a nice nucleus like you doing in a joint like this?

Irving M Shapiro1, Edward J Vresilovic, Makarand V Risbud.   

Abstract

This review challenges an earlier view that the intervertebral joint could not be classified as a diarthrodial joint and should remain as an amphiarthrosis. However, a careful analysis of the relevant literature and in light of more recent studies, it is clear that while some differences exist between the spinal articulation and the generic synovial joint, there are clear structural, functional and developmental similarities between the joints that in sum outweigh the differences. Further, since the intervertebral motion segment displays movement in three dimensions and the whole spine itself provides integrated rotatory movements, it is proposed that it should be classified not as an amphiarthrose, "a slightly moveable joint" but as a complex polyaxial joint. Hopefully, reclassification will encourage further analysis of the structure and function of the two types of overlapping joints and provide common new insights into diseases that afflict the many joints of the human skeleton. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 22197996      PMCID: PMC3278538          DOI: 10.1016/j.bone.2011.12.004

Source DB:  PubMed          Journal:  Bone        ISSN: 1873-2763            Impact factor:   4.398


  43 in total

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Review 2.  Human intervertebral disc: structure and function.

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Journal:  Clin Exp Immunol       Date:  1985-03       Impact factor: 4.330

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Authors:  K Yong-Hing; W H Kirkaldy-Willis
Journal:  Orthop Clin North Am       Date:  1983-07       Impact factor: 2.472

5.  Ultrastructural localization of hyaluronic acid in the synovium of the goat knee joint.

Authors:  Tadashi Yasui; Azuma Tsukise; Shogo Sakurai; Isao Habata; Wilfried Meyer; Yoshifumi Hirabayashi
Journal:  Ann Anat       Date:  2004-08       Impact factor: 2.698

Review 6.  The mechanobiology of articular cartilage development and degeneration.

Authors:  Dennis R Carter; Gary S Beaupré; Marcy Wong; R Lane Smith; Tom P Andriacchi; David J Schurman
Journal:  Clin Orthop Relat Res       Date:  2004-10       Impact factor: 4.176

7.  Prenatal and postnatal development of the cervical portion of the spine in the short-finned pilot whale Globicephala macrorhyncha.

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Journal:  Anat Rec       Date:  1981-05

8.  Elevation of cathepsin L levels in the synovial lining of rabbits with antigen-induced arthritis.

Authors:  D J Etherington; M A Taylor; B Henderson
Journal:  Br J Exp Pathol       Date:  1988-04

9.  The role of extracellular matrix in the formation of the sclerotome.

Authors:  M Solursh; M Fisher; S Meier; C T Singley
Journal:  J Embryol Exp Morphol       Date:  1979-12

10.  An immunoelectron microscope study of the organization of proteoglycan monomer, link protein, and collagen in the matrix of articular cartilage.

Authors:  A R Poole; I Pidoux; A Reiner; L Rosenberg
Journal:  J Cell Biol       Date:  1982-06       Impact factor: 10.539

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  22 in total

Review 1.  The role of HIF proteins in maintaining the metabolic health of the intervertebral disc.

Authors:  Elizabeth S Silagi; Ernestina Schipani; Irving M Shapiro; Makarand V Risbud
Journal:  Nat Rev Rheumatol       Date:  2021-06-03       Impact factor: 20.543

2.  TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression.

Authors:  Steven Tessier; Victoria A Tran; Olivia K Ottone; Emanuel J Novais; Alexandra Doolittle; Michael J DiMuzio; Irving M Shapiro; Makarand V Risbud
Journal:  Matrix Biol       Date:  2019-11-09       Impact factor: 11.583

Review 3.  Reconstruction of an in vitro niche for the transition from intervertebral disc development to nucleus pulposus regeneration.

Authors:  Mark Shoukry; Jingting Li; Ming Pei
Journal:  Stem Cells Dev       Date:  2013-02-15       Impact factor: 3.272

Review 4.  Glycosaminoglycan synthesis in the nucleus pulposus: Dysregulation and the pathogenesis of disc degeneration.

Authors:  Elizabeth S Silagi; Irving M Shapiro; Makarand V Risbud
Journal:  Matrix Biol       Date:  2018-03-01       Impact factor: 11.583

Review 5.  Molecular mechanisms of biological aging in intervertebral discs.

Authors:  Nam V Vo; Robert A Hartman; Prashanti R Patil; Makarand V Risbud; Dimitris Kletsas; James C Iatridis; Judith A Hoyland; Christine L Le Maitre; Gwendolyn A Sowa; James D Kang
Journal:  J Orthop Res       Date:  2016-08-12       Impact factor: 3.494

6.  Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting.

Authors:  Makarand V Risbud; Zachary R Schoepflin; Fackson Mwale; Rita A Kandel; Sibylle Grad; James C Iatridis; Daisuke Sakai; Judith A Hoyland
Journal:  J Orthop Res       Date:  2015-01-21       Impact factor: 3.494

7.  Fibronectin splice variation in human knee cartilage, meniscus and synovial membrane: observations in osteoarthritic knee.

Authors:  Carla R Scanzello; Dessislava Z Markova; Ana Chee; Yan Xiu; Sherrill L Adams; Greg Anderson; Miltiadis Zgonis; Ling Qin; Howard S An; Yejia Zhang
Journal:  J Orthop Res       Date:  2015-01-06       Impact factor: 3.494

Review 8.  Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissues.

Authors:  Cassie M Tran; Irving M Shapiro; Makarand V Risbud
Journal:  Matrix Biol       Date:  2013-04-06       Impact factor: 11.583

9.  Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.

Authors:  Zachary R Schoepflin; Irving M Shapiro; Makarand V Risbud
Journal:  J Bone Miner Res       Date:  2016-03-15       Impact factor: 6.741

10.  Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats.

Authors:  Qi Sun; Fa-Ming Tian; Fang Liu; Jia-Kang Fang; Yun-Peng Hu; Qiang-Qiang Lian; Zhuang Zhou; Liu Zhang
Journal:  Arthritis Res Ther       Date:  2021-05-28       Impact factor: 5.156

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