Literature DB >> 2219708

Comparative sequence of the helper component (HC) region of potato virus Y and a HC-defective strain, potato virus C.

D W Thornbury1, C A Patterson, J T Dessens, T P Pirone.   

Abstract

Potato virus C (PVC), a non-aphid transmissible strain of potato virus Y (PVY), was found to code for a protein (PVC-HC) which is similar in molecular weight and immunological reactivity to the helper component protein of PVY (PVY-HC). PVC-HC, however, was inactive with respect to its ability to effect aphid transmission of either PVC or PVY. The 5'-terminal 2.7-kb regions of PVC and PVY were sequenced. Within the HC region there was 92% nucleotide homology between the two strains; comparison of the derived amino acid sequences revealed 24 amino acid differences. Comparison of the PVC-HC sequence with that of five potyviruses revealed 2 amino acid changes which were specific to PVC-HC. These amino acids are prime targets for mutational analysis of HC activity.

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Year:  1990        PMID： 2219708     DOI： 10.1016/0042-6822(90)90356-v

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  15 in total

1.  Multiple Barriers to the Evolution of Alternative Gene Orders in a Positive-Strand RNA Virus.

Authors:  Anouk Willemsen; Mark P Zwart; Nicolas Tromas; Eszter Majer; José-Antonio Daròs; Santiago F Elena
Journal:  Genetics       Date:  2016-02-11       Impact factor: 4.562

Review 2.  The HCPro from the Potyviridae family: an enviable multitasking Helper Component that every virus would like to have.

Authors:  Adrián A Valli; Araiz Gallo; Bernardo Rodamilans; Juan José López-Moya; Juan Antonio García
Journal:  Mol Plant Pathol       Date:  2017-05-26       Impact factor: 5.663

3.  Debilitation of plant potyvirus infectivity by P1 proteinase-inactivating mutations and restoration by second-site modifications.

Authors:  J Verchot; J C Carrington
Journal:  J Virol       Date:  1995-03       Impact factor: 5.103

4.  Spontaneous mutagenesis of a plant potyvirus genome after insertion of a foreign gene.

Authors:  V V Dolja; K L Herndon; T P Pirone; J C Carrington
Journal:  J Virol       Date:  1993-10       Impact factor: 5.103

5.  Eggplant mild leaf mottle virus (EMLMV), a new putative member of the genus Ipomovirus that harbors an HC-Pro gene.

Authors:  Aviv Dombrovsky; Rumakanta Sapkota; Oded Lachman; Yehezkel Antignus
Journal:  Virus Genes       Date:  2011-11-16       Impact factor: 2.332

6.  Nucleotide sequences of the helper component-proteinase genes of aphid transmissible and non-transmissible isolates of turnip mosaic virus.

Authors:  H Nakashima; N Sako; K Hori
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

7.  Amino acid substitutions in the coat protein result in loss of insect transmissibility of a plant virus.

Authors:  P L Atreya; C D Atreya; T P Pirone
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205

8.  Nucleotide sequence of a Singapore isolate of zucchini yellow mosaic virus coat protein gene revealed an altered DAG motif.

Authors:  S C Lee; M Wu; S M Wong
Journal:  Virus Genes       Date:  1993-12       Impact factor: 2.332

9.  Mutational analysis of the helper component-proteinase gene of a potyvirus: effects of amino acid substitutions, deletions, and gene replacement on virulence and aphid transmissibility.

Authors:  C D Atreya; T P Pirone
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205

10.  Immunodetection of the plum pox virus helper component in infected plants and expression of its gene in transgenic plants.

Authors:  M Ravelonandro; O Peyruchaud; L Garrigue; G de Marcillac; J Dunez
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574
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