| Literature DB >> 22196928 |
Yixiu Li1, Zhong Chen, Ziming Feng, Yanan Yang, Jianshuang Jiang, Peicheng Zhang.
Abstract
Two new phenylethanoid glycosides 1 and 2 named leonoside E and leonoside F, and one new sesquiterpene glycoside (3) identified as 7α (H)-eudesmane-4,11 (12)-diene-3-one-2β-hydroxy-13-β-d-glucopyranoside, together with seven known glycosides (4-10), were isolated from the aerial part of Leonurus japonicus Houtt. Their structures were elucidated on the basis of spectroscopic data and chemical evidence. When tested in in vitro assays, compounds 1, 2, 4, and 6 exhibited potent hepatoprotective activity against d-galactosamine-induced toxicity in HL-7702 cells at concentration of 1×10(-5) M.Entities:
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Year: 2011 PMID： 22196928 DOI： 10.1016/j.carres.2011.10.034
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104