Literature DB >> 22196723

Metabolic connections during apoptotic cell engulfment.

Claudia Z Han1, Kodi S Ravichandran.   

Abstract

Billions of cells die via apoptosis every day and are swiftly removed. When a phagocyte engulfs an apoptotic cell, it essentially doubles its cellular contents, raising the question of how a phagocyte may manage the excess metabolic load. This Minireview discusses phagocyte cellular metabolism, the digestion of the ingested apoptotic cell, and the impact of these processes on engulfment.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 22196723      PMCID: PMC3254670          DOI: 10.1016/j.cell.2011.12.006

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  20 in total

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  60 in total

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