Literature DB >> 22194438

Aspects of deceased organ donation in paediatrics.

J Brierley1, A Hasan.   

Abstract

Organ transplantation offers children in acute or chronic severe organ failure similar opportunities to adults. However, while the number who might benefit is relatively low, significantly fewer cadaveric donors exist for any given child compared with an adult. Incompatible organ size and relatively low donation rates mean that despite living parental donation and innovations to reduce donated organ size, children die before organs become available. The severity of the UK situation is compounded by restrictions on paediatric living donation, uncertainties over the application of brain death criteria, and ethical concerns about the use of donation after circulatory death. The UK Department of Health's Organ Donation Task Force suggested the means by which the adult donor pool might be increased, recommending that outstanding ethical and legal issues be resolved, but made no specific recommendations about children.

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Year:  2012        PMID: 22194438     DOI: 10.1093/bja/aer405

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  3 in total

Review 1.  The promise of organ and tissue preservation to transform medicine.

Authors:  Sebastian Giwa; Jedediah K Lewis; Luis Alvarez; Robert Langer; Alvin E Roth; George M Church; James F Markmann; David H Sachs; Anil Chandraker; Jason A Wertheim; Martine Rothblatt; Edward S Boyden; Elling Eidbo; W P Andrew Lee; Bohdan Pomahac; Gerald Brandacher; David M Weinstock; Gloria Elliott; David Nelson; Jason P Acker; Korkut Uygun; Boris Schmalz; Brad P Weegman; Alessandro Tocchio; Greg M Fahy; Kenneth B Storey; Boris Rubinsky; John Bischof; Janet A W Elliott; Teresa K Woodruff; G John Morris; Utkan Demirci; Kelvin G M Brockbank; Erik J Woods; Robert N Ben; John G Baust; Dayong Gao; Barry Fuller; Yoed Rabin; David C Kravitz; Michael J Taylor; Mehmet Toner
Journal:  Nat Biotechnol       Date:  2017-06-07       Impact factor: 54.908

2.  Organ and tissue donation in a regional paediatric intensive care unit: evaluation of practice.

Authors:  Laura Carone; Shrirang Alurkar; Phoebe Kigozi; Harish Vyas
Journal:  Eur J Pediatr       Date:  2018-02-07       Impact factor: 3.183

3.  Evaluation of Pediatric Brain Death and Organ Donation: 10-Year Experience in a Pediatric Intensive Care Unit in Turkey.

Authors:  Faruk Ekinci; Dinçer Yıldızdaş; Özden Özgür Horoz; Faruk İncecik
Journal:  Turk Arch Pediatr       Date:  2021-11
  3 in total

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