Literature DB >> 22193888

The cell biology of TRIM5α.

Zana Lukic1, Edward M Campbell.   

Abstract

The tripartite motif (TRIM)-containing proteins are involved in many cellular functions such as cell signaling, apoptosis, cell differentiation, and immune modulation. TRIM5 proteins, including TRIM5α and TRIM-Cyp, are known to possess antiretroviral activity against many different retroviruses. Besides being retroviral restriction factors, TRIM5 proteins participate in other cellular functions that have recently emerged in the study of TRIM5α. In this review, we discuss properties of TRIM5α such as cytoplasmic body formation, protein turnover, and trafficking. Also, we discuss recent insights into innate immune modulation mediated by TRIM5α, highlighting the various functions TRIM5α has in cellular processes.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22193888      PMCID： PMC3501103          DOI： 10.1007/s11904-011-0102-8

Source DB:  PubMed          Journal:  Curr HIV/AIDS Rep        ISSN： 1548-3568            Impact factor:   5.071


  66 in total

1.  New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications.

Authors:  Stephen R Adams; Robert E Campbell; Larry A Gross; Brent R Martin; Grant K Walkup; Yong Yao; Juan Llopis; Roger Y Tsien
Journal:  J Am Chem Soc       Date:  2002-05-29       Impact factor: 15.419

2.  SS-A/Ro52, an autoantigen involved in CD28-mediated IL-2 production.

Authors:  Tomonori Ishii; Kei Ohnuma; Akikazu Murakami; Naruhiko Takasawa; Tadanori Yamochi; Satoshi Iwata; Masahiko Uchiyama; Nam H Dang; Hirotoshi Tanaka; Chikao Morimoto
Journal:  J Immunol       Date:  2003-04-01       Impact factor: 5.422

3.  Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1.

Authors:  David M Sayah; Elena Sokolskaja; Lionel Berthoux; Jeremy Luban
Journal:  Nature       Date:  2004-07-07       Impact factor: 49.962

4.  Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation.

Authors:  M Lamar Seibenhener; Jeganathan Ramesh Babu; Thangiah Geetha; Hing C Wong; N Rama Krishna; Marie W Wooten
Journal:  Mol Cell Biol       Date:  2004-09       Impact factor: 4.272

5.  Role of the promyelocytic leukemia body in the dynamic interaction between the androgen receptor and steroid receptor coactivator-1 in living cells.

Authors:  Omar J Rivera; Chung S Song; Victoria E Centonze; James D Lechleiter; Bandana Chatterjee; Arun K Roy
Journal:  Mol Endocrinol       Date:  2003-01

6.  Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha.

Authors:  Shuo Dong; David L Stenoien; Jihui Qiu; Michael A Mancini; David J Tweardy
Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272

7.  Size, position and dynamic behavior of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly.

Authors:  Christopher H Eskiw; Graham Dellaire; Joe S Mymryk; David P Bazett-Jones
Journal:  J Cell Sci       Date:  2003-09-16       Impact factor: 5.285

8.  The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys.

Authors:  Matthew Stremlau; Christopher M Owens; Michel J Perron; Michael Kiessling; Patrick Autissier; Joseph Sodroski
Journal:  Nature       Date:  2004-02-26       Impact factor: 49.962

9.  The tripartite motif family identifies cell compartments.

Authors:  A Reymond; G Meroni; A Fantozzi; G Merla; S Cairo; L Luzi; D Riganelli; E Zanaria; S Messali; S Cainarca; A Guffanti; S Minucci; P G Pelicci; A Ballabio
Journal:  EMBO J       Date:  2001-05-01       Impact factor: 11.598

10.  Visualization of the intracellular behavior of HIV in living cells.

Authors:  David McDonald; Marie A Vodicka; Ginger Lucero; Tatyana M Svitkina; Gary G Borisy; Michael Emerman; Thomas J Hope
Journal:  J Cell Biol       Date:  2002-11-04       Impact factor: 10.539
View more
  6 in total

1.  TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction.

Authors:  Sabrina Imam; Sarah Talley; Rachel S Nelson; Adarsh Dharan; Christopher O'Connor; Thomas J Hope; Edward M Campbell
Journal:  J Virol       Date:  2016-01-13       Impact factor: 5.103

Review 2.  Visualizing HIV-1 Capsid and Its Interactions with Antivirals and Host Factors.

Authors:  Morganne Wilbourne; Peijun Zhang
Journal:  Viruses       Date:  2021-02-04       Impact factor: 5.818

3.  TRIM22: A Diverse and Dynamic Antiviral Protein.

Authors:  Clayton J Hattlmann; Jenna N Kelly; Stephen D Barr
Journal:  Mol Biol Int       Date:  2012-05-08

4.  Life at the mesoscale: the self-organised cytoplasm and nucleoplasm.

Authors:  Richard P Sear; Ignacio Pagonabarraga; Andrew Flaus
Journal:  BMC Biophys       Date:  2015-02-25       Impact factor: 4.778

5.  Ubiquitination-coupled liquid phase separation regulates the accumulation of the TRIM family of ubiquitin ligases into cytoplasmic bodies.

Authors:  Takafumi Tozawa; Kohichi Matsunaga; Tetsuro Izumi; Naotake Shigehisa; Takamasa Uekita; Masato Taoka; Tohru Ichimura
Journal:  PLoS One       Date:  2022-08-05       Impact factor: 3.752

Review 6.  Interplay between viruses and host sumoylation pathways.

Authors:  Roger D Everett; Chris Boutell; Benjamin G Hale
Journal:  Nat Rev Microbiol       Date:  2013-04-29       Impact factor: 60.633
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.