OBJECTIVE: The increasing incidence of pediatric Crohn's disease (CD) is well known in Western countries in the last two decades. This study was conducted to delineate the trends of incidence during this period and clinical patterns of pediatric CD in Taiwan. METHODS: All children admitted to National Taiwan University Hospital between 1990 and 2009 who met the Porto Criteria for CD were included. Annual enrollment and clinical characteristics were retrospectively reviewed. The incidence was calculated by dividing the number of index cases by total hospitalized pediatric cases to minimize the bias caused by the growing number of hospitalized patients there. We quoted data and statistics from the Department of Health, Executive Yuan, Taiwan, and Accounting and Statistics, Executive Yuan, Taiwan, to present the social-economic changes in Taiwan in the recent decades. RESULTS: The cumulative hospital-based incidence of CD rose from 13.2 per 100,000 to 25.4 per 100,000 children admitted to this hospital in the past two decades. The median age of diagnosis in the first decade of this study was less than that of the second decade. The other study parameters, including gender, disease activity at diagnosis, duration from disease onset to diagnosis, anatomic location and disease behavior, and symptoms at diagnosis, were not different. CONCLUSIONS: This study showed that the hospital-based incidence of pediatric CD has been increasing in Taiwan in recent decades. Factors contributing to such an increase could be physicians' awareness of the disease, easier access to health care, and environmental factors.
OBJECTIVE: The increasing incidence of pediatric Crohn's disease (CD) is well known in Western countries in the last two decades. This study was conducted to delineate the trends of incidence during this period and clinical patterns of pediatric CD in Taiwan. METHODS: All children admitted to National Taiwan University Hospital between 1990 and 2009 who met the Porto Criteria for CD were included. Annual enrollment and clinical characteristics were retrospectively reviewed. The incidence was calculated by dividing the number of index cases by total hospitalized pediatric cases to minimize the bias caused by the growing number of hospitalized patients there. We quoted data and statistics from the Department of Health, Executive Yuan, Taiwan, and Accounting and Statistics, Executive Yuan, Taiwan, to present the social-economic changes in Taiwan in the recent decades. RESULTS: The cumulative hospital-based incidence of CD rose from 13.2 per 100,000 to 25.4 per 100,000 children admitted to this hospital in the past two decades. The median age of diagnosis in the first decade of this study was less than that of the second decade. The other study parameters, including gender, disease activity at diagnosis, duration from disease onset to diagnosis, anatomic location and disease behavior, and symptoms at diagnosis, were not different. CONCLUSIONS: This study showed that the hospital-based incidence of pediatric CD has been increasing in Taiwan in recent decades. Factors contributing to such an increase could be physicians' awareness of the disease, easier access to health care, and environmental factors.
Authors: Scott S Short; Marla C Dubinsky; Shervin Rabizadeh; Sharmayne Farrior; Dror Berel; Philip K Frykman Journal: J Pediatr Surg Date: 2013-06 Impact factor: 2.545
Authors: Khalid AlSaleem; Mohammad Issa El Mouzan; Omar I Saadah; Bader AlSaleem; Abdulrahman Al-Hussaini; Mohammed Hassosa; Al-Mehaidib Ali; Mohammed Othman Banemai; Hana Halaby; Mohammed El Edreesi Journal: Ann Saudi Med Date: 2015 Jan-Feb Impact factor: 1.526
Authors: Jae Young Choe; Sujin Choi; Ki Hwan Song; Hyo-Jeong Jang; Kwang-Hae Choi; Dae Yong Yi; Suk Jin Hong; Jun Hyun Hwang; Seung-Man Cho; Young Jin Kim; Byung-Ho Choe; Ben Kang Journal: Front Pediatr Date: 2022-01-04 Impact factor: 3.418