Literature DB >> 22191583

Has nanotechnology led to improved therapeutic outcomes?

Stephanie Bosselmann1, Robert O Williams.   

Abstract

Nanoparticulate drug delivery systems provide new opportunities for solving issues associated with problematic drugs or disease states and have, therefore, created great expectations in the field of drug delivery. This review focuses on the potential benefits of nanoparticles compared with other conventional delivery systems. Several nanoparticulate drug delivery systems have already been marketed or are currently under development and are presented in this review. Results from clinical trials demonstrate that nanoparticulate formulations generally enable superior therapeutic outcomes than compared with standard formulations. Therefore, the implementation of nanotechnology in drug delivery represents an important advance with substantial potential to improve therapeutic effectiveness and increase patient's quality of life.

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Year:  2012        PMID: 22191583     DOI: 10.3109/03639045.2011.597764

Source DB:  PubMed          Journal:  Drug Dev Ind Pharm        ISSN: 0363-9045            Impact factor:   3.225


  6 in total

1.  CDER risk assessment exercise to evaluate potential risks from the use of nanomaterials in drug products.

Authors:  Celia N Cruz; Katherine M Tyner; Lydia Velazquez; Kenneth C Hyams; Abigail Jacobs; Arthur B Shaw; Wenlei Jiang; Robert Lionberger; Peter Hinderling; Yoon Kong; Paul C Brown; Tapash Ghosh; Caroline Strasinger; Sandra Suarez-Sharp; Don Henry; Maat Van Uitert; Nakissa Sadrieh; Elaine Morefield
Journal:  AAPS J       Date:  2013-03-20       Impact factor: 4.009

2.  Optimization of the fabrication of novel stealth PLA-based nanoparticles by dispersion polymerization using D-optimal mixture design.

Authors:  Simeon K Adesina; Scott A Wight; Emmanuel O Akala
Journal:  Drug Dev Ind Pharm       Date:  2013-09-23       Impact factor: 3.225

3.  Role of GABA and serotonin coupled chitosan nanoparticles in enhanced hepatocyte proliferation.

Authors:  J Shilpa; B T Roshni; R Chinthu; C S Paulose
Journal:  J Mater Sci Mater Med       Date:  2012-09-08       Impact factor: 3.896

Review 4.  A Review of Currently Available Fenofibrate and Fenofibric Acid Formulations.

Authors:  Hua Ling; John T Luoma; Daniel Hilleman
Journal:  Cardiol Res       Date:  2013-05-09

5.  Development of Pelubiprofen Tromethamine with Improved Gastrointestinal Safety and Absorption.

Authors:  Ji Yeon Park; Dong Ho Oh; Sang-Wook Park; Bo Ram Chae; Chul Woo Kim; Sang Heon Han; Hyeon Jong Shin; Soo Bin Yeom; Da Yeong Lee; Min Kyu Park; Sang-Eun Park; Jun-Bom Park; Kyung-Tae Lee
Journal:  Pharmaceutics       Date:  2021-05-18       Impact factor: 6.321

Review 6.  Drug Delivery Strategies for Curcumin and Other Natural Nrf2 Modulators of Oxidative Stress-Related Diseases.

Authors:  Nina Katarina Grilc; Matej Sova; Julijana Kristl
Journal:  Pharmaceutics       Date:  2021-12-12       Impact factor: 6.321

  6 in total

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