AIM: The aim of the study is to assess the efficacy of Acute Normovolaemic Haemodilution (ANH) in reducing the perioperative homologous transfusion, to compare the results of acute normovolaemic haemodilution and homologous blood transfusion in terms of Hb%, PCV%, and to assess the cost effectiveness of ANH with homologous transfusion. METHODS:30 healthy patients between the age of 14-70 years, who required a maxillofacial surgical procedure under general anaesthesia with haemoglobin level of 12 gm% or above, PCV 30% or above and where postoperative blood transfusion was not expected to be beyond one pint, were selected. The patients were randomly divided into two groups of 15 patients each. The group I patients were subjected to ANH and the group II patients were transfused 1 pint of compatible banked, homologous blood and mean haemoglobin and PCV was compared in 1st, 3rd and 7th post-operative day in both the groups. RESULT: Patients who received ANH had p < 0.05 than patients who received homologous transfusion by using student's paired t-test in terms of Hb% and PCV%. CONCLUSION: It was concluded that ANH is more effective compared to homologous bleeding time.
RCT Entities:
AIM: The aim of the study is to assess the efficacy of Acute Normovolaemic Haemodilution (ANH) in reducing the perioperative homologous transfusion, to compare the results of acute normovolaemic haemodilution and homologous blood transfusion in terms of Hb%, PCV%, and to assess the cost effectiveness of ANH with homologous transfusion. METHODS: 30 healthy patients between the age of 14-70 years, who required a maxillofacial surgical procedure under general anaesthesia with haemoglobin level of 12 gm% or above, PCV 30% or above and where postoperative blood transfusion was not expected to be beyond one pint, were selected. The patients were randomly divided into two groups of 15 patients each. The group I patients were subjected to ANH and the group II patients were transfused 1 pint of compatible banked, homologous blood and mean haemoglobin and PCV was compared in 1st, 3rd and 7th post-operative day in both the groups. RESULT: Patients who received ANH had p < 0.05 than patients who received homologous transfusion by using student's paired t-test in terms of Hb% and PCV%. CONCLUSION: It was concluded that ANH is more effective compared to homologous bleeding time.
Entities:
Keywords:
Acute normovolaemic haemodilution; Blood transfusion; Pectoralis major myocutaneous flap; Supra omohyoid neck dissection
Authors: G Sanders; N Mellor; K Rickards; A Rushton; I Christie; J Nicholl; A Copplestone; K Hosie Journal: Br J Anaesth Date: 2004-10-01 Impact factor: 9.166