Literature DB >> 22189810

Secondary hyperparathyroidism status in Brazil: Brazilian census of parathyroidectomy.

Rodrigo Bueno de Oliveira1, Eduardo Neves da Silva, Douglas Moraes Freire Charpinel, José Edevanilson Barros Gueiros, Carolina Lara Neves, Elisa de Albuquerque Sampaio, Fellype de Carvalho Barreto, Cristina Karohl, Melani Custódio Ribeiro, Rosa Maria Affonso Moysés, Vanda Jorgetti, Aluizio Barbosa de Carvalho.   

Abstract

INTRODUCTION: Secondary hyperparathyroidism (SHP) is a common and serious complication of chronic kidney disease (CKD), with a negative impact on morbidity and mortality. Despite advances in the clinical management of SHP, treatment failure still occurs in a significant number of patients. In such cases, parathyroidectomy (PTx) is indicated.
OBJECTIVE: To have an overview of the prevalence of severe SHP and of its surgical treatment in hemodialysis (HD) patients in Brazil.
METHODS: This was an observational and descriptive study. Data were obtained from questionnaires posted to 660 dialysis units (DU).
RESULTS: Results are expressed in absolute values and percentages, or means and standard deviation, as appropriate. 226 (34%) DU answered the questionnaire, providing data about 32,264 HD patients. The prevalence rate of severe SHP (PTH > 1,000 pg/mL) was 10.7 % (n = 3,463). 68 hospitals countrywide perform PTX. Around 40% of them are university centers. 49 (21.7%) DU reported not to have a specialized medical center to refer their patients with severe SHP. 74 (33%) DU reported that the time interval between surgery indication and its performance was over 6 months. The main recognized obstacles to surgery performance were: difficulty to perform the preoperative exams, lack of head and neck surgeons and the long waiting time.
CONCLUSIONS: Although severe SHP is highly prevalent in Brazil, a significant number of patients do not have access to PTx. Better public health policies and liaison between nephrologists and head and neck surgeons are urgently required to change this reality.

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Year:  2011        PMID: 22189810

Source DB:  PubMed          Journal:  J Bras Nefrol        ISSN: 0101-2800


  8 in total

1.  Effect of parathyroidectomy on bone tissue biomarkers and body composition in patients with chronic kidney disease and secondary hyperparathyroidism.

Authors:  Flavia Ramos de Siqueira; Karin Carneiro de Oliveira; Wagner Vasques Dominguez; César Augusto Madid Truyts; Rosa Maria Affonso Moysés; Luciene Machado Dos Reis; Vanda Jorgetti
Journal:  Eur J Clin Nutr       Date:  2021-01-18       Impact factor: 4.016

2.  Treatment of Hyperparathyroidism (SHPT).

Authors:  Fabiana Rodrigues Hernandes; Patrícia Goldenstein; Melani Ribeiro Custódio
Journal:  J Bras Nefrol       Date:  2021-12-03

3.  International burden of chronic kidney disease and secondary hyperparathyroidism: a systematic review of the literature and available data.

Authors:  Elizabeth Hedgeman; Loren Lipworth; Kimberly Lowe; Rajiv Saran; Thy Do; Jon Fryzek
Journal:  Int J Nephrol       Date:  2015-03-31

4.  Parathyroidectomy in the treatment of BMD-DRC Brazil: many limitations, but still fundamental.

Authors:  Lilian P F Carmo
Journal:  J Bras Nefrol       Date:  2018-11-14

5.  The impact of cinacalcet in the mineral metabolism markers of patients on dialysis with severe secondary hyperparathyroidism.

Authors:  Sérgio Gardano Elias Bucharles; Fellype Carvalho Barreto; Miguel Carlos Riella
Journal:  J Bras Nefrol       Date:  2019-07-18

6.  Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?

Authors:  Murilo Catafesta das Neves; Augusto Riedel Abrahão; Marcio Abrahão; Marcello Rosano; Lillian Andrade da Rocha; Hanna Karla Andrade Guapyassu Machado; Rodrigo Oliveira Santos
Journal:  Braz J Otorhinolaryngol       Date:  2020-11-16

7.  Risk factors for severe hypocalcemia after parathyroidectomy in dialysis patients with secondary hyperparathyroidism.

Authors:  Xiaoliang Sun; Xiaoqing Zhang; Yao Lu; Ling Zhang; Meng Yang
Journal:  Sci Rep       Date:  2018-05-17       Impact factor: 4.379

8.  High ankle-brachial index predicts cardiovascular events and mortality in hemodialysis patients with severe secondary hyperparathyroidism.

Authors:  Alinie Pichone; Gabriela Campos; Maurilo Leite; Carlos Perez Gomes
Journal:  J Bras Nefrol       Date:  2021 Oct-Dec
  8 in total

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