Literature DB >> 22187975

Outcomes and pulmonary function in living lobar lung transplant donors.

Fengshi Chen1, Takuji Fujinaga, Tsuyoshi Shoji, Makoto Sonobe, Toshihiko Sato, Hiroaki Sakai, Toru Bando, Hiroshi Date.   

Abstract

Successful living-donor lobar lung transplantation (LDLLT) largely depends on donor outcome; however, there are few studies that have assessed outcomes of LDLLT donors, particularly pulmonary function. We investigated the outcomes and pulmonary function after donor lobectomy in LDLLT donors. Retrospective evaluation of consecutive 33 LDLLT donors was performed. Preoperative characteristics and perioperative and postoperative variables were investigated. Evaluation of pulmonary function 3, 6 and 12 months after donor lobectomy was performed prospectively. All donors were well alive after donor lobectomies. Morbidity was found in five donors (15%). Postoperative complications consisted of re-accumulation of pleural effusion requiring readmission in three donors and prolonged air leakage in two donors. Sacrifice of pulmonary arteries was performed in 20 donors (61%) with 1.4 ± 0.6 branches. Forced vital capacity was 77.8 ± 6.1%, 84.8 ± 6.0% and 89.4 ± 6.6% of the preoperative value 3, 6 and 12 months after donor lobectomy, respectively. Forced expiratory volume in 1 s was 80.5 ± 7.8%, 85.6 ± 8.9% and 89.3 ± 8.7% of the preoperative value 3, 6, and 12 months postoperatively. Living-donor lobectomy was performed with low morbidity. Pulmonary function even after lobectomy was better preserved than expected.
© 2011 The Authors. Transplant International © 2011 European Society for Organ Transplantation.

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Year:  2011        PMID: 22187975     DOI: 10.1111/j.1432-2277.2011.01401.x

Source DB:  PubMed          Journal:  Transpl Int        ISSN: 0934-0874            Impact factor:   3.782


  4 in total

Review 1.  Three-dimensional image in lung transplantation.

Authors:  Toyofumi F Chen-Yoshikawa; Hiroshi Date
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-10-16

Review 2.  Living-related lung transplantation.

Authors:  Hiroshi Date
Journal:  J Thorac Dis       Date:  2017-09       Impact factor: 2.895

3.  Live related donor lobar lung transplantation recipients surviving well over a decade: still an option in times of advanced donor management.

Authors:  Prashant N Mohite; Aron F Popov; Magdi H Yacoub; Andre R Simon
Journal:  J Cardiothorac Surg       Date:  2013-03-07       Impact factor: 1.637

4.  Practical guidelines: lung transplantation in patients with cystic fibrosis.

Authors:  T O Hirche; C Knoop; H Hebestreit; D Shimmin; A Solé; J S Elborn; H Ellemunter; P Aurora; M Hogardt; T O F Wagner
Journal:  Pulm Med       Date:  2014-03-30
  4 in total

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