Literature DB >> 22187952

Comparison late cutaneous complications between exposure to sulfur mustard and nerve agents.

Seyed Naser Emadi1, Jafar Aslani, Zohreh Poursaleh, Morteza Izadi, Mohammadreza Soroush, Mohammad Kafashi, Seyed Ali Alavinia, Hossein Bakhshi, Amir Karimi, Kourosh Momtaz-Manesh, Ali Akbar Babaei, Alireza Esmaili, Babak Raygan, Seyed Emad Emadi, Farhang Babamahmoodi, Seyed Abolfazl Emadi.   

Abstract

BACKGROUND: Iraq used chemical weapons against thousands of Iranian militaries and civilians. This study aimed to compare the chronic cutaneous side effects of exposure to sulfur mustard (SM) with nerve agents (NA).
METHODS: The study enrolled 154 SM exposed cases and 175 (NA) exposed cases. Presence of any late cutaneous manifestations was evaluated by a dermatologist via prior history of acute cutaneous complications extracted from medical achieves.
RESULTS: only 18.1% mustard exposed group was asymptomatic compared to 62.4% nerve agent exposures. Mustard and non-mustard scars, intertrigo, xerosis, cherry angioma, hyper pigmentation, pilar keratosis, poikiloderma, and malignant tumors were significantly more frequent in mustard exposed patients (p < 0.05). Nerve agent exposed patients experienced significantly more frequent occurrence of acne a seborrheic dermatitis and tinea versicolor.
CONCLUSIONS: Mustard induced dermaltologic lesions were more common and specific than (NA) skin injuries. (NA) cause few psychocutaneous disorders like acne and seborrheic dermatitis in addition to psychological stress disorders.

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Year:  2011        PMID: 22187952     DOI: 10.3109/15569527.2011.641196

Source DB:  PubMed          Journal:  Cutan Ocul Toxicol        ISSN: 1556-9527            Impact factor:   1.820


  6 in total

1.  Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice.

Authors:  Neera Tewari-Singh; Anil K Jain; Swetha Inturi; Carl W White; Rajesh Agarwal
Journal:  PLoS One       Date:  2013-06-24       Impact factor: 3.240

2.  Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.

Authors:  Neera Tewari-Singh; Anil K Jain; David J Orlicky; Carl W White; Rajesh Agarwal
Journal:  PLoS One       Date:  2014-01-08       Impact factor: 3.240

3.  Common malignant cutaneous conditions among albinos in Kenya.

Authors:  Seyed Emad Emadi; Andrew Juma Suleh; Farhang Babamahmoodi; Fatemeh Ahangarkani; Vanessa Betty Chelimo; Beatrice Mutai; Seyyed Reza Raeeskarami; Alireza Ghanadan; Seyed Naser Emadi
Journal:  Med J Islam Repub Iran       Date:  2017-01-11

4.  The Quality of Life of Mustard Gas Victims: A Systematic Review.

Authors:  Mojtaba Satkin; Mostafa Ghanei; Abbas Ebadi; Sahar Allahverdi; Mahdi Elikaei
Journal:  Tanaffos       Date:  2017

5.  Defining the timing of 25(OH)D rescue following nitrogen mustard exposure.

Authors:  Lopa M Das; Amy M Binko; Zachary P Traylor; Lori Duesler; Kurt Q Lu
Journal:  Cutan Ocul Toxicol       Date:  2017-08-08       Impact factor: 1.820

6.  Long-term Health Outcomes Among Survivors Exposed to Sulfur Mustard in Iran.

Authors:  Hossein Amini; Masoud Solaymani-Dodaran; Batool Mousavi; Seyed Nooredin Alam Beladi; Mohammad Reza Soroush; Jamileh Abolghasemi; Amir Vahedian-Azimi; Mahmoud Salesi; Paul C Guest; Amirhossein Sahebkar; Mostafa Ghanei
Journal:  JAMA Netw Open       Date:  2020-12-01
  6 in total

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