Literature DB >> 22187844

Intralesional curettage, with phenol and cement as adjuvants, for low-grade intramedullary chondrosarcoma of the long bones.

Luigi Di Giorgio1, Georgios Touloupakis, Fabrizio Vitullo, Luca Sodano, Marco Mastantuono, Ciro Villani.   

Abstract

The authors conducted a retrospective study on 23 patients (12 females and 11 males) with low-grade intramedullary chondrosarcoma of a long bone, treated with intralesional curettage, phenolization and cementation. The use of phenol was supported by an in vitro study, the use of bone cement by clinical studies. A consensus has been growing that this type of tumours should be treated less aggressively. The average age of the patients was 445 years (range: 29 to 71). The mean follow-up period was 6.2 years (range: 2.5 to 11 years). After 6 months the average Musculoskeletal Tumor Society (MSTS) score was 76.8% of 30, the best possible score (range: 61% to 87%). After 12 months this score increased to 89.8% (range: 63% to 100%). Complications were: one recurrence (43%), treated with a tumour prosthesis, and 3 fractures (13%). The authors strongly support this new technique, all the more as it still allows for a more radical approach, if necessary. They stress the importance of a strict follow-up by a multidisciplinary team, in order to treat local recurrences and (rarely) metastases.

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Year:  2011        PMID: 22187844

Source DB:  PubMed          Journal:  Acta Orthop Belg        ISSN: 0001-6462            Impact factor:   0.500


  8 in total

1.  Intralesional treatment versus wide resection for central low-grade chondrosarcoma of the long bones.

Authors:  Edwin F Dierselhuis; Krista A Goulding; Martin Stevens; Paul C Jutte
Journal:  Cochrane Database Syst Rev       Date:  2019-03-07

2.  Do Orthopaedic Oncologists Agree on the Diagnosis and Treatment of Cartilage Tumors of the Appendicular Skeleton?

Authors:  Tomas Zamora; Julio Urrutia; Daniel Schweitzer; Pedro Pablo Amenabar; Eduardo Botello
Journal:  Clin Orthop Relat Res       Date:  2017-02-15       Impact factor: 4.176

Review 3.  Treatment strategies for central low-grade chondrosarcoma of long bones: a systematic review of the literature and meta-analysis.

Authors:  S S Shemesh; J D Acevedo-Nieves; J Pretell-Mazzini
Journal:  Musculoskelet Surg       Date:  2017-10-06

4.  Surgical therapy of benign and low-grade malignant intramedullary chondroid lesions of the distal femur: intralesional resection and bone cement filling with or without osteosynthesis.

Authors:  Georg W Omlor; Vera Lohnherr; Pit Hetto; Simone Gantz; Jörg Fellenberg; Christian Merle; Thorsten Guehring; Burkhard Lehner
Journal:  Strategies Trauma Limb Reconstr       Date:  2018-11-03

5.  Survival and prognostic factors in conventional G1 chondrosarcoma.

Authors:  Julian Fromm; Alexander Klein; Andrea Baur-Melnyk; Thomas Knösel; Lars Lindner; Christof Birkenmaier; Falk Roeder; Volkmar Jansson; Hans Roland Dürr
Journal:  World J Surg Oncol       Date:  2019-09-03       Impact factor: 2.754

6.  Early postoperative compilations of bone filling in curettage defects.

Authors:  Clark J Chen; Earl W Brien
Journal:  J Orthop Surg Res       Date:  2019-08-16       Impact factor: 2.359

7.  Enchondromas and atypical cartilaginous tumors at the proximal humerus treated with intralesional resection and bone cement filling with or without osteosynthesis: retrospective analysis of 42 cases with 6 years mean follow-up.

Authors:  Georg W Omlor; Vera Lohnherr; Jessica Lange; Simone Gantz; Christian Merle; Joerg Fellenberg; Patric Raiss; Burkhard Lehner
Journal:  World J Surg Oncol       Date:  2018-07-13       Impact factor: 2.754

8.  Survival and prognostic factors in conventional central chondrosarcoma.

Authors:  Julian Fromm; Alexander Klein; Andrea Baur-Melnyk; Thomas Knösel; Lars Lindner; Christof Birkenmaier; Falk Roeder; Volkmar Jansson; Hans Roland Dürr
Journal:  BMC Cancer       Date:  2018-08-24       Impact factor: 4.430

  8 in total

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