Literature DB >> 22187843

The effect of Luque-Galveston fusion on curve, respiratory function and quality of life in Duchenne muscular dystrophy.

Nick Van Opstal1, Christophe Verlinden, Jan Myncke, Nathalie Goemans, Pierre Moens.   

Abstract

The aim of this retrospective study was to evaluate the long-term effect of the Luque-Galveston spinal fusion in Duchenne muscular dystrophy (DMD) patients. Twenty patients had undergone this operation at a mean age of 153 years (surgical group, A). The correction of their scoliosis amounted to +/- 55.8%, after an average follow-up period of 3 years. This is in accordance with the literature. The authors would therefore advise to perform spinal fusion in an early stage of the disease, once a rapid evolution of the scoliosis is seen. The decline of respiratory function slightly diminished after surgery, but not significantly. This means that no expectations should be made to improve respiratory function, as respiratory function decline continues relentlessly. Most authors agree with this statement. Patient satisfaction after surgery was relatively high, mainly because of an improved sitting balance, but only 60% of the questionnaires were available. Twenty-five other patients were not operated upon (non-surgical group, B). They had better results at ages 153 and 183, but this was mainly due to the fact that group B contained more benign cases according to the Oda classification.

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Year:  2011        PMID: 22187843

Source DB:  PubMed          Journal:  Acta Orthop Belg        ISSN: 0001-6462            Impact factor:   0.500


  4 in total

1.  Tailor-made management of thoracic scoliosis with cervical hyperextension in muscular dystrophy.

Authors:  A Angelliaume; L Harper; A Lalioui; A Delgove; Y Lefèvre
Journal:  Eur Spine J       Date:  2017-06-07       Impact factor: 3.134

Review 2.  Cardiovascular Disease in Duchenne Muscular Dystrophy: Overview and Insight Into Novel Therapeutic Targets.

Authors:  Taylor I Schultz; Frank J Raucci; Fadi N Salloum
Journal:  JACC Basic Transl Sci       Date:  2022-03-09

Review 3.  Assessment and management of respiratory function in patients with Duchenne muscular dystrophy: current and emerging options.

Authors:  Antonella LoMauro; Maria Grazia D'Angelo; Andrea Aliverti
Journal:  Ther Clin Risk Manag       Date:  2015-09-28       Impact factor: 2.423

4.  Nanolipodendrosome-loaded glatiramer acetate and myogenic differentiation 1 as augmentation therapeutic strategy approaches in muscular dystrophy.

Authors:  Ehsan Afzal; Saba Zakeri; Peyman Keyhanvar; Meisam Bagheri; Parvin Mahjoubi; Mahtab Asadian; Nogol Omoomi; Mohammad Dehqanian; Negar Ghalandarlaki; Tahmineh Darvishmohammadi; Fatemeh Farjadian; Mohammad Sadegh Golvajoee; Shadi Afzal; Maryam Ghaffari; Reza Ahangari Cohan; Amin Gravand; Mehdi Shafiee Ardestani
Journal:  Int J Nanomedicine       Date:  2013-08-08
  4 in total

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