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Literature DB >> 22184007

PKM2: a gatekeeper between growth and survival.

Isaac Harris¹, Susan McCracken, Tak Wah Mak.

Abstract

Entities: Species

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Year: 2011 PMID： 22184007 PMCID： PMC3292300 DOI： 10.1038/cr.2011.203

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

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16 in total

1. Pyruvate kinase M2 is a phosphotyrosine-binding protein.

Authors: Heather R Christofk; Matthew G Vander Heiden; Ning Wu; John M Asara; Lewis C Cantley
Journal: Nature Date: 2008-03-13 Impact factor: 49.962

2. The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2.

Authors: Gilles A Spoden; Dieter Morandell; Daniela Ehehalt; Marc Fiedler; Pidder Jansen-Dürr; Martin Hermann; Werner Zwerschke
Journal: J Cell Biochem Date: 2009-05-15 Impact factor: 4.429

3. Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.

Authors: Dimitrios Anastasiou; George Poulogiannis; John M Asara; Matthew B Boxer; Jian-kang Jiang; Min Shen; Gary Bellinger; Atsuo T Sasaki; Jason W Locasale; Douglas S Auld; Craig J Thomas; Matthew G Vander Heiden; Lewis C Cantley
Journal: Science Date: 2011-11-03 Impact factor: 47.728

4. The dual activity of pyruvate kinase type M2 from chromatin extracts of neoplastic cells.

Authors: Jan Ignacak; Maria Barbara Stachurska
Journal: Comp Biochem Physiol B Biochem Mol Biol Date: 2003-03 Impact factor: 2.231

5. Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death.

Authors: Attila Steták; Réka Veress; Judit Ovádi; Péter Csermely; György Kéri; Axel Ullrich
Journal: Cancer Res Date: 2007-02-15 Impact factor: 12.701

6. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer.

Authors: Charles J David; Mo Chen; Marcela Assanah; Peter Canoll; James L Manley
Journal: Nature Date: 2009-12-13 Impact factor: 49.962

7. Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.

Authors: Taro Hitosugi; Sumin Kang; Matthew G Vander Heiden; Tae-Wook Chung; Shannon Elf; Katherine Lythgoe; Shaozhong Dong; Sagar Lonial; Xu Wang; Georgia Z Chen; Jianxin Xie; Ting-Lei Gu; Roberto D Polakiewicz; Johannes L Roesel; Titus J Boggon; Fadlo R Khuri; D Gary Gilliland; Lewis C Cantley; Jonathan Kaufman; Jing Chen
Journal: Sci Signal Date: 2009-11-17 Impact factor: 8.192

8. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.

Authors: Heather R Christofk; Matthew G Vander Heiden; Marian H Harris; Arvind Ramanathan; Robert E Gerszten; Ru Wei; Mark D Fleming; Stuart L Schreiber; Lewis C Cantley
Journal: Nature Date: 2008-03-13 Impact factor: 49.962

9. Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription.

Authors: Jungwoon Lee; Hye Kyoung Kim; Yong-Mahn Han; Jungho Kim
Journal: Int J Biochem Cell Biol Date: 2007-11-29 Impact factor: 5.085

10. Regulation of cell proliferation by interleukin-3-induced nuclear translocation of pyruvate kinase.

Authors: Akemi Hoshino; John A Hirst; Hodaka Fujii
Journal: J Biol Chem Date: 2007-04-19 Impact factor: 5.157

24 in total

1. Altered glycometabolism affects both clinical features and prognosis of triple-negative and neoadjuvant chemotherapy-treated breast cancer.

Authors: Tieying Dong; Xinmei Kang; Zhaoliang Liu; Shu Zhao; Wenjie Ma; Qijia Xuan; Hang Liu; Zhipeng Wang; Qingyuan Zhang
Journal: Tumour Biol Date: 2015-12-29

2. Oncoprotein HBXIP induces PKM2 via transcription factor E2F1 to promote cell proliferation in ER-positive breast cancer.

Authors: Bo-Wen Liu; Tian-Jiao Wang; Lei-Lei Li; Lu Zhang; Yun-Xia Liu; Jin-Yan Feng; Yue Wu; Fei-Fei Xu; Quan-Sheng Zhang; Ming-Zhu Bao; Wei-Ying Zhang; Li-Hong Ye
Journal: Acta Pharmacol Sin Date: 2018-06-20 Impact factor: 6.150

Review 3. Emerging roles of aerobic glycolysis in breast cancer.

Authors: Z Wu; J Wu; Q Zhao; S Fu; J Jin
Journal: Clin Transl Oncol Date: 2019-07-29 Impact factor: 3.405

4. Oxidative stress stimulates invasive potential in rat C6 and human U-87 MG glioblastoma cells via activation and cross-talk between PKM2, ENPP2 and APE1 enzymes.

Authors: Ravi P Cholia; Monisha Dhiman; Raj Kumar; Anil K Mantha
Journal: Metab Brain Dis Date: 2018-05-02 Impact factor: 3.584

5. Comparison of Hepatic NRF2 and Aryl Hydrocarbon Receptor Binding in 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Treated Mice Demonstrates NRF2-Independent PKM2 Induction.

Authors: Rance Nault; Claire M Doskey; Kelly A Fader; Cheryl E Rockwell; Tim Zacharewski
Journal: Mol Pharmacol Date: 2018-05-11 Impact factor: 4.436

10. Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin.

Authors: Rance Nault; Kelly A Fader; Mathew P Kirby; Shaimaa Ahmed; Jason Matthews; A Daniel Jones; Sophia Y Lunt; Timothy R Zacharewski
Journal: Toxicol Sci Date: 2015-11-17 Impact factor: 4.849