Literature DB >> 22183500

Protocol management of late-stage pressure ulcers: a 5-year retrospective study of 101 consecutive patients with 179 ulcers.

David L Larson1, Kristen A Hudak, William P Waring, Merle R Orr, Kevin Simonelic.   

Abstract

BACKGROUND: Despite a 12 to 82 percent pressure ulcer recurrence rate, no standard protocol exists for postoperative management. The authors reviewed a single surgeon's experience using a standard protocol: surgery and immediate reconstruction regardless of nutrition, intraoperative bone culture guiding postoperative antibiotic use, and hospital admission for 3 weeks of flat bedrest before graduated sitting.
METHODS: A 5-year retrospective chart review was performed on consecutive surgically treated pressure ulcers. A search of billing records identified 101 patients with 179 ulcers. Data abstracted included demographics, comorbidities, location and stage of ulcers, treatment history with outcomes, and laboratory data.
RESULTS: Seventy-nine percent of the patients were men with a mean age of 49.4 years. Of 179 ulcers, 49.7 percent were ischial, 26.8 percent were sacral, and 19 percent were trochanteric; 87.7 percent of ulcers were stage 4. Primary closure was performed on 45.8 percent; others underwent flap closure. There was no correlation between positive bone cultures and recurrence or complications. The overall recurrence rate was 16.8 percent at a mean period of 435.9 days. New ulcer occurrence was 14.5 percent and the complication rate was 17.3 percent. Admission prealbumin and albumin did not correlate with recurrence or complication. Mean follow-up was 629 days.
CONCLUSIONS: A standard clinical pathway for pressure ulcer treatment improves long-term outcomes; the authors' protocol's validity is supported by low recurrence and complication rates. Nutritional data do not predict outcome. Intraoperative bone cultures are the most valid method of diagnosing osteomyelitis; results should not delay definitive treatment. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

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Year:  2012        PMID: 22183500     DOI: 10.1097/PRS.0b013e3182442197

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  11 in total

Review 1.  Osteomyelitis Complicating Sacral Pressure Ulcers: Whether or Not to Treat With Antibiotic Therapy.

Authors:  Darren Wong; Paul Holtom; Brad Spellberg
Journal:  Clin Infect Dis       Date:  2019-01-07       Impact factor: 9.079

2.  The operative treatment of pressure sores in the pelvic region: A 10-year period overview.

Authors:  János Jósvay; András Klauber; Béla Both; Péter B Kelemen; Zsombor Z Varga; Pál Cs Pesthy
Journal:  J Spinal Cord Med       Date:  2014-10-09       Impact factor: 1.985

3.  Improving Pressure Ulcer Reconstruction: Our Protocol and the COP (Cone of Pressure) Flap.

Authors:  Francesco Gargano; Lee Edstrom; Karen Szymanski; Scott Schmidt; Jack Bevivino; Richard Zienowicz; Jennifer Stark; Helena O Taylor; Silvio Podda; Paul Liu
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-03-30

4.  Seeing is Believing? Preoperative Magnetic Resonance Imaging for Pressure Ulcers: Implications for Surgical Management.

Authors:  James McCarthy; Emily Hartmann; Michael L Bentz; Venkat K Rao; Young Jee; David Rivedal; Samuel O Poore
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-03-28

5.  Flap Reconstruction for Pressure Ulcers: An Outcomes Analysis.

Authors:  Ravinder Bamba; James J Madden; Ashley N Hoffman; Justine S Kim; Wesley P Thayer; Lillian B Nanney; Marcia E Spear
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-01-18

6.  Pressure Ulcer-Related Pelvic Osteomyelitis: A Neglected Disease?

Authors:  Phani Bodavula; Stephen Y Liang; Jiami Wu; Paige VanTassell; Jonas Marschall
Journal:  Open Forum Infect Dis       Date:  2015-08-06       Impact factor: 3.835

7.  A novel model of human skin pressure ulcers in mice.

Authors:  Andrés A Maldonado; Lara Cristóbal; Javier Martín-López; Mar Mallén; Natalio García-Honduvilla; Julia Buján
Journal:  PLoS One       Date:  2014-10-13       Impact factor: 3.240

8.  Pressure ulcer-related pelvic osteomyelitis: evaluation of a two-stage surgical strategy (debridement, negative pressure therapy and flap coverage) with prolonged antimicrobial therapy.

Authors:  Johan Andrianasolo; Tristan Ferry; Fabien Boucher; Joseph Chateau; Hristo Shipkov; Fatiha Daoud; Evelyne Braun; Claire Triffault-Fillit; Thomas Perpoint; Frédéric Laurent; Alain-Ali Mojallal; Christian Chidiac; Florent Valour
Journal:  BMC Infect Dis       Date:  2018-04-10       Impact factor: 3.090

Review 9.  Spinal Infections: An Update.

Authors:  Andreas G Tsantes; Dimitrios V Papadopoulos; Georgia Vrioni; Spyridon Sioutis; George Sapkas; Ahmed Benzakour; Thami Benzakour; Andrea Angelini; Pietro Ruggieri; Andreas F Mavrogenis
Journal:  Microorganisms       Date:  2020-03-27

10.  Comparative study between fasciocutaneous and myocutaneous flaps in the surgical treatment of pressure ulcers of the sacral region.

Authors:  D Oksman; O M de Almeida; R G de Arruda; M L M de Almeida; F S do Carmo
Journal:  JPRAS Open       Date:  2018-02-26
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