Literature DB >> 22183330

The mechanism of fenretinide (4-HPR) inhibition of β-carotene monooxygenase 1. New suspect for the visual side effects of fenretinide.

Eugenia Poliakov1, Alexander Gubin, James Laird, Susan Gentleman, Robert G Salomon, T Michael Redmond.   

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Year:  2012        PMID： 22183330     DOI： 10.1007/978-1-4614-0631-0_23

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


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  6 in total

1.  Fenretinide induces ubiquitin-dependent proteasomal degradation of stearoyl-CoA desaturase in human retinal pigment epithelial cells.

Authors:  William Samuel; R Krishnan Kutty; Todd Duncan; Camasamudram Vijayasarathy; Bryan C Kuo; Krysten M Chapa; T Michael Redmond
Journal:  J Cell Physiol       Date:  2014-08       Impact factor: 6.384

2.  Fenretinide inhibits vitamin A formation from β-carotene and regulates carotenoid levels in mice.

Authors:  Anthony P Miller; Molly Black; Jaume Amengual
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2021-11-04       Impact factor: 4.698

3.  Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.

Authors:  Laura Zemany; Sanjay Bhanot; Odile D Peroni; Susan F Murray; Pedro M Moraes-Vieira; Angela Castoldi; Prasad Manchem; Shuling Guo; Brett P Monia; Barbara B Kahn
Journal:  Diabetes       Date:  2014-12-18       Impact factor: 9.461

4.  Inhibitory effects of fenretinide metabolites N-[4-methoxyphenyl]retinamide (MPR) and 4-oxo-N-(4-hydroxyphenyl)retinamide (3-keto-HPR) on fenretinide molecular targets β-carotene oxygenase 1, stearoyl-CoA desaturase 1 and dihydroceramide Δ4-desaturase 1.

Authors:  Eugenia Poliakov; William Samuel; Todd Duncan; Danielle B Gutierrez; Nathan L Mata; T Michael Redmond
Journal:  PLoS One       Date:  2017-04-27       Impact factor: 3.240

5.  Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function.

Authors:  Philip D Kiser; Jianye Zhang; Aditya Sharma; Juan M Angueyra; Alexander V Kolesnikov; Mohsen Badiee; Gregory P Tochtrop; Junzo Kinoshita; Neal S Peachey; Wei Li; Vladimir J Kefalov; Krzysztof Palczewski
Journal:  J Gen Physiol       Date:  2018-03-02       Impact factor: 4.086

Review 6.  β-carotene in Obesity Research: Technical Considerations and Current Status of the Field.

Authors:  Johana Coronel; Ivan Pinos; Jaume Amengual
Journal:  Nutrients       Date:  2019-04-13       Impact factor: 5.717
  6 in total

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