OBJECTIVE: To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. METHODS: A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infection were excluded by appropriate tests. Clinical presentation and laboratory parameters were studied. RESULTS: Medical records of 213 individuals who satisfied the inclusion criteria were reviewed. Anaemia was seen in 65 (30.5%), leucopenia in 38 (17.8%) and thrombocytopenia in 184 (86.4%) patients. Aspartate and alanine aminotransferases were elevated in 86 (40.4%), and 89 (41.9%) patients respectively. Hypoalbuminemia was observed in 157 (73.6%) cases. Elevated serum creatinine was noted in in 59 (27.5%) patients. Creatine kinase was elevated in 30 out of 59 patients (50.8%). Overall, 107 (50.2%) patients fulfilled WHO criteria for severe malaria. None of the patients succumbed to the disease. CONCLUSIONS: P. vivax malaria is a potentially severe disease, and the term "benign" tertian malaria is a misnomer. Despite significant morbidity, with timely and appropriate treatment P. vivax malaria has an excellent outcome.
OBJECTIVE: To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. METHODS: A retrospective analysis was performed of all patients of P. vivaxmalaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infection were excluded by appropriate tests. Clinical presentation and laboratory parameters were studied. RESULTS: Medical records of 213 individuals who satisfied the inclusion criteria were reviewed. Anaemia was seen in 65 (30.5%), leucopenia in 38 (17.8%) and thrombocytopenia in 184 (86.4%) patients. Aspartate and alanine aminotransferases were elevated in 86 (40.4%), and 89 (41.9%) patients respectively. Hypoalbuminemia was observed in 157 (73.6%) cases. Elevated serum creatinine was noted in in 59 (27.5%) patients. Creatine kinase was elevated in 30 out of 59 patients (50.8%). Overall, 107 (50.2%) patients fulfilled WHO criteria for severe malaria. None of the patients succumbed to the disease. CONCLUSIONS:P. vivaxmalaria is a potentially severe disease, and the term "benign" tertian malaria is a misnomer. Despite significant morbidity, with timely and appropriate treatment P. vivaxmalaria has an excellent outcome.
Authors: Devendra Bansal; Anushree Acharya; Praveen K Bharti; Mohamed H Abdelraheem; Ashraf Elmalik; Salem Abosalah; Fahmi Y Khan; Mohamed ElKhalifa; Hargobinder Kaur; Pradyumna K Mohapatra; Rakesh Sehgal; Mohammed A Idris; Jagadish Mahanta; Neeru Singh; Hamza A Babiker; Ali A Sultan Journal: Am J Trop Med Hyg Date: 2017-09-28 Impact factor: 2.345
Authors: Spinello Antinori; Alberto Corona; Anna Lisa Ridolfo; Laura Galimberti; Davide Ricaboni; Laura Milazzo; Mario Corbellino Journal: Malar J Date: 2016-02-19 Impact factor: 2.979