Literature DB >> 22182585

CNTF and retina.

Rong Wen1, Weng Tao, Yiwen Li, Paul A Sieving.   

Abstract

Ciliary neurotrophic factor (CNTF) is one of the most studied neurotrophic factors for neuroprotection of the retina. A large body of evidence demonstrates that CNTF promotes rod photoreceptor survival in almost all animal models. Recent studies indicate that CNTF also promotes cone photoreceptor survival and cone outer segment regeneration in the degenerating retina and improves cone function in dogs with congenital achromotopsia. In addition, CNTF is a neuroprotective factor and an axogenesis factor for retinal ganglion cells (RGCs). This review focuses on the effects of exogenous CNTF on photoreceptors and RGCs in the mammalian retina and the potential clinical application of CNTF for retinal degenerative diseases.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 22182585      PMCID: PMC3288688          DOI: 10.1016/j.preteyeres.2011.11.005

Source DB:  PubMed          Journal:  Prog Retin Eye Res        ISSN: 1350-9462            Impact factor:   21.198


  143 in total

Review 1.  Information processing in the primate retina: circuitry and coding.

Authors:  G D Field; E J Chichilnisky
Journal:  Annu Rev Neurosci       Date:  2007       Impact factor: 12.449

2.  CNGB3 achromatopsia with progressive loss of residual cone function and impaired rod-mediated function.

Authors:  Naheed Wali Khan; Bernd Wissinger; Susanne Kohl; Paul A Sieving
Journal:  Invest Ophthalmol Vis Sci       Date:  2007-08       Impact factor: 4.799

3.  CNTF negatively regulates the phototransduction machinery in rod photoreceptors: implication for light-induced photostasis plasticity.

Authors:  Rong Wen; Ying Song; Yun Liu; Yiwen Li; Lian Zhao; Alan M Laties
Journal:  Adv Exp Med Biol       Date:  2008       Impact factor: 2.622

4.  Exogenous CNTF stimulates axon regeneration of retinal ganglion cells partially via endogenous CNTF.

Authors:  Adrienne Müller; Thomas G Hauk; Marco Leibinger; Ralf Marienfeld; Dietmar Fischer
Journal:  Mol Cell Neurosci       Date:  2009-03-28       Impact factor: 4.314

5.  Achromatopsia: the CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14.

Authors:  Wojciech Wiszniewski; Richard Alan Lewis; James R Lupski
Journal:  Hum Genet       Date:  2007-01-31       Impact factor: 4.132

6.  Regulation of cytokine signaling components in developing rat retina correlates with transient inhibition of rod differentiation by CNTF.

Authors:  Daniel Hertle; Michael Schleichert; Andreas Steup; Matthias Kirsch; Hans-Dieter Hofmann
Journal:  Cell Tissue Res       Date:  2008-07-30       Impact factor: 5.249

Review 7.  CNTF: a target therapeutic for obesity-related metabolic disease?

Authors:  Vance B Matthews; Mark A Febbraio
Journal:  J Mol Med (Berl)       Date:  2008-01-22       Impact factor: 4.599

8.  Effect of CNTF on retinal ganglion cell survival in experimental glaucoma.

Authors:  Mary Ellen Pease; Donald J Zack; Cynthia Berlinicke; Kristen Bloom; Frances Cone; Yuxia Wang; Ronald L Klein; William W Hauswirth; Harry A Quigley
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-12-05       Impact factor: 4.799

9.  Intraocular CNTF reduces vision in normal rats in a dose-dependent manner.

Authors:  Trevor J McGill; Glen T Prusky; Robert M Douglas; Douglas Yasumura; Michael T Matthes; George Nune; Kate Donohue-Rolfe; Haidong Yang; Diana Niculescu; William W Hauswirth; Sergej V Girman; Raymond D Lund; Jacque L Duncan; Matthew M LaVail
Journal:  Invest Ophthalmol Vis Sci       Date:  2007-12       Impact factor: 4.799

10.  Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography.

Authors:  Stephan Nickell; Paul S-H Park; Wolfgang Baumeister; Krzysztof Palczewski
Journal:  J Cell Biol       Date:  2007-05-29       Impact factor: 10.539

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  79 in total

Review 1.  Cell replacement and visual restoration by retinal sheet transplants.

Authors:  Magdalene J Seiler; Robert B Aramant
Journal:  Prog Retin Eye Res       Date:  2012-07-05       Impact factor: 21.198

Review 2.  Glaucoma management: relative value and place in therapy of available drug treatments.

Authors:  Deepak Sambhara; Ahmad A Aref
Journal:  Ther Adv Chronic Dis       Date:  2014-01       Impact factor: 5.091

Review 3.  A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders.

Authors:  Muayyad R Al-Ubaidi; Muna I Naash; Shannon M Conley
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-12-17       Impact factor: 4.799

4.  Chapter 6 - Restoring Vision to the Blind: Neuroprotection.

Authors: 
Journal:  Transl Vis Sci Technol       Date:  2014-12-30       Impact factor: 3.283

5.  High speed adaptive optics ophthalmoscopy with an anamorphic point spread function.

Authors:  Jing Lu; Boyu Gu; Xiaolin Wang; Yuhua Zhang
Journal:  Opt Express       Date:  2018-05-28       Impact factor: 3.894

6.  Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments.

Authors:  Songhua Li; Kota Sato; William C Gordon; Michael Sendtner; Nicolas G Bazan; Minghao Jin
Journal:  J Biol Chem       Date:  2018-08-16       Impact factor: 5.157

7.  A Novel Neuroprotective Small Molecule for Glial Cell Derived Neurotrophic Factor Induction and Photoreceptor Rescue.

Authors:  Petr Baranov; Hong Lin; Kathryn McCabe; David Gale; Shenshen Cai; Burke Lieppman; Dwight Morrow; Phoebe Lei; Justin Liao; Michael Young
Journal:  J Ocul Pharmacol Ther       Date:  2017-04-25       Impact factor: 2.671

8.  Spectral-domain optical coherence tomography staging and autofluorescence imaging in achromatopsia.

Authors:  Jonathan P Greenberg; Jerome Sherman; Sandrine A Zweifel; Royce W S Chen; Tobias Duncker; Susanne Kohl; Britta Baumann; Bernd Wissinger; Lawrence A Yannuzzi; Stephen H Tsang
Journal:  JAMA Ophthalmol       Date:  2014-04-01       Impact factor: 7.389

9.  A new immunodeficient pigmented retinal degenerate rat strain to study transplantation of human cells without immunosuppression.

Authors:  Magdalene J Seiler; Robert B Aramant; Melissa K Jones; Dave L Ferguson; Elizabeth C Bryda; Hans S Keirstead
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-05-13       Impact factor: 3.117

10.  A highly efficient catalyst for oxime ligation and hydrazone-oxime exchange suitable for bioconjugation.

Authors:  Mohammad Rashidian; Mohammad M Mahmoodi; Rachit Shah; Jonathan K Dozier; Carston R Wagner; Mark D Distefano
Journal:  Bioconjug Chem       Date:  2013-03-06       Impact factor: 4.774

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