Literature DB >> 22179620

Pd-Catalyzed asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)indoles.

Ying Duan1, Mu-Wang Chen, Qing-An Chen, Chang-Bin Yu, Yong-Gui Zhou.   

Abstract

A series of 2-substituted 3-(toluenesulfonamidoalkyl)indoles was synthesized by application of (EtO)(2)POH or iodine as the catalyst, and was hydrogenated using chiral Pd catalyst, giving the 2,3-disubstituted indolines with up to 97% ee.

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Year:  2011        PMID： 22179620     DOI： 10.1039/c1ob06777j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Advances in Stereoconvergent Catalysis from 2005 to 2015: Transition-Metal-Mediated Stereoablative Reactions, Dynamic Kinetic Resolutions, and Dynamic Kinetic Asymmetric Transformations.

Authors:  Vikram Bhat; Eric R Welin; Xuelei Guo; Brian M Stoltz
Journal:  Chem Rev       Date:  2017-02-06       Impact factor: 60.622

2.  Highly diastereo- and enantioselective CuH-catalyzed synthesis of 2,3-disubstituted indolines.

Authors:  Erhad Ascic; Stephen L Buchwald
Journal:  J Am Chem Soc       Date:  2015-04-06       Impact factor: 15.419

3.  Pd-catalyzed asymmetric hydrogenation of fluorinated aromatic pyrazol-5-ols via capture of active tautomers.

Authors:  Zhang-Pei Chen; Mu-Wang Chen; Lei Shi; Chang-Bin Yu; Yong-Gui Zhou
Journal:  Chem Sci       Date:  2015-03-31       Impact factor: 9.825
  3 in total

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