Literature DB >> 22179031

Osteoarthritis year 2011 in review: biology.

M Lotz1.   

Abstract

This review is focused on advances in understanding the biology of joint homeostasis and osteoarthritis (OA) pathogenesis mechanisms that have led to proof of concept studies on new therapeutic approaches. The three selected topics include angiogenesis in joint tissues, biomechanics and joint lubrication and mitochondrial dysfunction. This new information represents progress in the integration of mechanisms that control multiple aspects of OA pathophysiology. Copyright Â
© 2011 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 22179031      PMCID： PMC3288592          DOI： 10.1016/j.joca.2011.11.015

Source DB:  PubMed          Journal:  Osteoarthritis Cartilage        ISSN： 1063-4584            Impact factor:   6.576


  52 in total

Review 1.  Linking functional decline of telomeres, mitochondria and stem cells during ageing.

Authors:  Ergün Sahin; Ronald A Depinho
Journal:  Nature       Date:  2010-03-25       Impact factor: 49.962

Review 2.  Physiological functions of autophagy.

Authors:  Noboru Mizushima
Journal:  Curr Top Microbiol Immunol       Date:  2009       Impact factor: 4.291

3.  Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis.

Authors:  Beatriz Caramés; Noboru Taniguchi; Shuhei Otsuki; Francisco J Blanco; Martin Lotz
Journal:  Arthritis Rheum       Date:  2010-03

Review 4.  New insights in synovial angiogenesis.

Authors:  Zoltán Szekanecz; Timea Besenyei; György Paragh; Alisa E Koch
Journal:  Joint Bone Spine       Date:  2009-12-21       Impact factor: 4.929

Review 5.  Disease modifying osteoarthritis drugs: facing development challenges and choosing molecular targets.

Authors:  Marie-Pierre Hellio Le Graverand-Gastineau
Journal:  Curr Drug Targets       Date:  2010-05       Impact factor: 3.465

6.  Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.

Authors:  Robert Terkeltaub; Bing Yang; Martin Lotz; Ru Liu-Bryan
Journal:  Arthritis Rheum       Date:  2011-07

7.  Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes.

Authors:  J Kim; M Xu; R Xo; A Mates; G L Wilson; A W Pearsall; V Grishko
Journal:  Osteoarthritis Cartilage       Date:  2009-10-01       Impact factor: 6.576

8.  N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis.

Authors:  Shuji Nakagawa; Yuji Arai; Osam Mazda; Tsunao Kishida; Kenji A Takahashi; Kei Sakao; Masazumi Saito; Kuniaki Honjo; Jiro Imanishi; Toshikazu Kubo
Journal:  J Orthop Res       Date:  2010-02       Impact factor: 3.494

9.  Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.

Authors:  David E Harrison; Randy Strong; Zelton Dave Sharp; James F Nelson; Clinton M Astle; Kevin Flurkey; Nancy L Nadon; J Erby Wilkinson; Krystyna Frenkel; Christy S Carter; Marco Pahor; Martin A Javors; Elizabeth Fernandez; Richard A Miller
Journal:  Nature       Date:  2009-07-08       Impact factor: 49.962

10.  The impact of anterior cruciate ligament injury on lubricin metabolism and the effect of inhibiting tumor necrosis factor alpha on chondroprotection in an animal model.

Authors:  K A Elsaid; J T Machan; K Waller; B C Fleming; G D Jay
Journal:  Arthritis Rheum       Date:  2009-10
View more
  18 in total

Review 1.  Future nanomedicine for the diagnosis and treatment of osteoarthritis.

Authors:  Lauren R Eichaker; Hongsik Cho; Craig L Duvall; Thomas A Werfel; Karen A Hasty
Journal:  Nanomedicine (Lond)       Date:  2014-07       Impact factor: 5.307

2.  Bevacizumab, an anti-vascular endothelial growth factor antibody, inhibits osteoarthritis.

Authors:  Toshihiro Nagai; Masato Sato; Miyuki Kobayashi; Munetaka Yokoyama; Yoshiki Tani; Joji Mochida
Journal:  Arthritis Res Ther       Date:  2014-09-18       Impact factor: 5.156

3.  Elevated expression of periostin in human osteoarthritic cartilage and its potential role in matrix degradation via matrix metalloproteinase-13.

Authors:  Mukundan Attur; Qing Yang; Kohei Shimada; Yuki Tachida; Hiroyuki Nagase; Paolo Mignatti; Lauren Statman; Glyn Palmer; Thorsten Kirsch; Frank Beier; Steven B Abramson
Journal:  FASEB J       Date:  2015-06-19       Impact factor: 5.191

4.  Unicompartmental osteoarthritis: an integrated biomechanical and biological approach as alternative to metal resurfacing.

Authors:  M Marcacci; S Zaffagnini; E Kon; G M Marcheggiani Muccioli; A Di Martino; B Di Matteo; T Bonanzinga; F Iacono; G Filardo
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2013-01-31       Impact factor: 4.342

5.  The synovial microenvironment of osteoarthritic joints alters RNA-seq expression profiles of human primary articular chondrocytes.

Authors:  Eric A Lewallen; Carolina A Bonin; Xin Li; Jay Smith; Marcel Karperien; A Noelle Larson; David G Lewallen; Simon M Cool; Jennifer J Westendorf; Aaron J Krych; Alexey A Leontovich; Hee-Jeong Im; Andre J van Wijnen
Journal:  Gene       Date:  2016-07-01       Impact factor: 3.688

6.  Systemic neutralization of TGF-β attenuates osteoarthritis.

Authors:  Liang Xie; Francis Tintani; Xiao Wang; Fengfeng Li; Gehua Zhen; Tao Qiu; Mei Wan; Janet Crane; Qianming Chen; Xu Cao
Journal:  Ann N Y Acad Sci       Date:  2016-02-02       Impact factor: 5.691

7.  Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis.

Authors:  Maria D Mayan; Raquel Gago-Fuentes; Paula Carpintero-Fernandez; Patricia Fernandez-Puente; Purificacion Filgueira-Fernandez; Noa Goyanes; Virginijus Valiunas; Peter R Brink; Gary S Goldberg; Francisco J Blanco
Journal:  Ann Rheum Dis       Date:  2013-11-13       Impact factor: 19.103

8.  Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis.

Authors:  Gehua Zhen; Chunyi Wen; Xiaofeng Jia; Yu Li; Janet L Crane; Simon C Mears; Frederic B Askin; Frank J Frassica; Weizhong Chang; Jie Yao; John A Carrino; Andrew Cosgarea; Dmitri Artemov; Qianming Chen; Zhihe Zhao; Xuedong Zhou; Lee Riley; Paul Sponseller; Mei Wan; William Weijia Lu; Xu Cao
Journal:  Nat Med       Date:  2013-05-19       Impact factor: 53.440

9.  Effect of hyaluronic acids as chondroprotective in experimental model of osteoarthrosis.

Authors:  Marcello Zaia Oliveira; Mauro Batista Albano; Mario Massatomo Namba; Luiz Antônio Munhoz da Cunha; Renan Rodrigues de Lima Gonçalves; Edvaldo Silva Trindade; Lucas Ferrari Andrade; Leandro Vidigal
Journal:  Rev Bras Ortop       Date:  2014-02-12

10.  Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis.

Authors:  Yoshiaki Ito; Tokio Matsuzaki; Fumiaki Ayabe; Sho Mokuda; Ryota Kurimoto; Takahide Matsushima; Yusuke Tabata; Maiko Inotsume; Hiroki Tsutsumi; Lin Liu; Masahiro Shinohara; Yoko Tanaka; Ryo Nakamichi; Keiichiro Nishida; Martin K Lotz; Hiroshi Asahara
Journal:  Nat Commun       Date:  2021-07-06       Impact factor: 14.919
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.