Literature DB >> 22178699

Production and first use of 153SmCl3-ion exchange resin capsule formulation for assessing gastrointestinal motility.

Chai-Hong Yeong1, Basri Johan Jeet Abdullah, Kwan-Hoong Ng, Lip-Yong Chung, Khean-Lee Goh, Sazilah Ahmad Sarji, Alan Christopher Perkins.   

Abstract

We produced an enteric-coated gelatine capsule containing neutron-activated (153)Sm-labelled resin beads for use in gastrointestinal motility studies. In vitro test in simulated gastrointestinal environment and in vivo study on volunteers were performed. Scintigraphic images were acquired from ten volunteers over 24h while blood and urine samples were collected to monitor the presence of (153)Sm. All the capsules remained intact in stomach. This proved to be a safe and practical oral capsule formulation for whole gut transit scintigraphy.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22178699     DOI： 10.1016/j.apradiso.2011.11.056

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  9 in total

1.  Optimization of Scatter Correction Method in Samarium-153 Single-photon Emission Computed Tomography using Triple-Energy Window: A Monte Carlo Simulation Study.

Authors:  Hicham Asmi; Farida Bentayeb; Youssef Bouzekraoui; Faustino Bonutti
Journal:  Indian J Nucl Med       Date:  2020-07-01

Review 2.  Gastro-retentive drug delivery systems: a recent update on clinical pertinence and drug delivery.

Authors:  Supratim Das; Sukhbir Kaur; Vineet Kumar Rai
Journal:  Drug Deliv Transl Res       Date:  2021-01-05       Impact factor: 4.617

3.  Gamma scintigraphic study of the hydrodynamically balanced matrix tablets of Metformin HCl in rabbits.

Authors:  Mahboubeh Razavi; Hamed Karimian; Chai Hong Yeong; Sazilah Ahmad Sarji; Lip Yong Chung; Shaik Nyamathulla; Mohamed Ibrahim Noordin
Journal:  Drug Des Devel Ther       Date:  2015-06-19       Impact factor: 4.162

4.  Gamma scintigraphic evaluation of floating gastroretentive tablets of metformin HCl using a combination of three natural polymers in rabbits.

Authors:  Mahboubeh Razavi; Hamed Karimian; Chai Hong Yeong; Lip Yong Chung; Shaik Nyamathulla; Mohamed Ibrahim Noordin
Journal:  Drug Des Devel Ther       Date:  2015-08-06       Impact factor: 4.162

5.  Gastroretentive behavior of orally administered radiolabeled tamarind seed formulations in rabbits validated by gamma scintigraphy.

Authors:  Mahboubeh Razavi; Hamed Karimian; Chai Hong Yeong; Mehran Fadaeinasab; Si Lay Khaing; Lip Yong Chung; Didi Erwandi B Mohamad Haron; Mohamed Ibrahim Noordin
Journal:  Drug Des Devel Ther       Date:  2016-12-19       Impact factor: 4.162

6.  Comparison of Image Quality of Different Radionuclides Technetium-99m, Samarium-153, and Iodine-123.

Authors:  Youssef Bouzekraoui; Farida Bentayeb; Hicham Asmi; Faustino Bonutti
Journal:  Indian J Nucl Med       Date:  2019 Jul-Sep

7.  Neutron Activated Samarium-153 Microparticles for Transarterial Radioembolization of Liver Tumour with Post-Procedure Imaging Capabilities.

Authors:  Nurul Ab Aziz Hashikin; Chai-Hong Yeong; Basri Johan Jeet Abdullah; Kwan-Hoong Ng; Lip-Yong Chung; Rehir Dahalan; Alan Christopher Perkins
Journal:  PLoS One       Date:  2015-09-18       Impact factor: 3.240

8.  Neutron-activated biodegradable samarium-153 acetylacetonate-poly-L-lactic acid microspheres for intraarterial radioembolization of hepatic tumors.

Authors:  Yin-How Wong; Hun-Yee Tan; Azahari Kasbollah; Basri Johan Jeet Abdullah; Rajendra Udyavara Acharya; Chai-Hong Yeong
Journal:  World J Exp Med       Date:  2020-03-30

9.  Preparation and In Vitro Evaluation of Neutron-Activated, Theranostic Samarium-153-Labeled Microspheres for Transarterial Radioembolization of Hepatocellular Carcinoma and Liver Metastasis.

Authors:  Yin How Wong; Hun Yee Tan; Azahari Kasbollah; Basri Johan Jeet Abdullah; Chai Hong Yeong
Journal:  Pharmaceutics       Date:  2019-11-12       Impact factor: 6.321
  9 in total

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