| Literature DB >> 22178113 |
Justyna Korycka1, Agnieszka Łach, Elżbieta Heger, Dżamila M Bogusławska, Marcin Wolny, Monika Toporkiewicz, Katarzyna Augoff, Jan Korzeniewski, Aleksander F Sikorski.
Abstract
Palmitoylation is one of the most common posttranslational lipid modifications of proteins and we now know quite a lot about it. However, the state of knowledge about the enzymes that catalyze this process is clearly insufficient. This review is focused on 23 human DHHC genes and their products - protein palmitoyltransferases. Here we describe mainly the structure and function of these proteins, but also, to a lesser degree, what the substrates of the enzymes are and whether they are related to various diseases. The main aim of this review was to catalogue existing information concerning the human DHHC family of genes/proteins, making them and their functions easier to understand.Entities:
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Year: 2011 PMID： 22178113 DOI： 10.1016/j.ejcb.2011.09.013
Source DB: PubMed Journal: Eur J Cell Biol ISSN： 0171-9335 Impact factor: 4.492