Amitabha Ray1, Margot P Cleary. 1. The Hormel Institute, University of Minnesota, 801-16th Avenue NE, Austin, MN 55912, USA.
Abstract
OBJECTIVES: To evaluate the laboratory diagnosis aspects of obesity-related health problems with special reference to postmenopausal breast cancer. DESIGN AND METHODS: We conducted a systemic search of the literature primarily from the PubMed to obtain the relevant data. RESULTS: Obesity is associated with the dysregulations of a number of body components such as blood constituents, extracellular matrix, and hormones/growth factors axes, which could be utilized for early diagnosis. CONCLUSIONS: Obesity-related disorders including breast cancer have emerged as major health problems in almost all the nations. There is a need to elucidate different biochemical markers that are being used in the clinics or have the potential for such use. A precise understanding of the complex pathologies related with obesity is useful in prevention, early diagnosis and overall clinical management.
OBJECTIVES: To evaluate the laboratory diagnosis aspects of obesity-related health problems with special reference to postmenopausal breast cancer. DESIGN AND METHODS: We conducted a systemic search of the literature primarily from the PubMed to obtain the relevant data. RESULTS:Obesity is associated with the dysregulations of a number of body components such as blood constituents, extracellular matrix, and hormones/growth factors axes, which could be utilized for early diagnosis. CONCLUSIONS:Obesity-related disorders including breast cancer have emerged as major health problems in almost all the nations. There is a need to elucidate different biochemical markers that are being used in the clinics or have the potential for such use. A precise understanding of the complex pathologies related with obesity is useful in prevention, early diagnosis and overall clinical management.
Authors: Erin D Giles; Elizabeth A Wellberg; David P Astling; Steven M Anderson; Ann D Thor; Sonali Jindal; Aik-Choon Tan; Pepper S Schedin; Paul S Maclean Journal: Cancer Res Date: 2012-12-07 Impact factor: 12.701