OBJECTIVE: The objective of this study was to assess the effectiveness of 0.5% ropivacaine used for parasternal intercostal blocks for postoperative analgesia in pediatric patients undergoing cardiac surgery. DESIGN: A randomized, controlled, prospective, double-blind study. SETTING: A tertiary care teaching hospital. PARTICIPANTS: Thirty children scheduled for cardiac surgery with a median sternotomy. INTERVENTIONS: A 0.5% ropivacaine injection with 5 doses of 0.5 to 2.0 mL on each side in the 2nd to 6th parasternal intercostal space with a total dose of ropivacaine below 5 mg/kg or the same volume of saline before sternal wound closure. MEASUREMENTS AND MAIN RESULTS: The time to extubation was significantly lower in patients administered the parasternal blocks with ropivacaine than in the control group; the mean values were 2.66 hours and 5.31 hours, respectively (p < 0.001). The pain scores were lower in the ropivacaine group compared with the saline group; mean values were 2.20 for the ropivacaine group and 4.83 for the saline group on a scale of 10. The cumulative fentanyl dose requirement over a 24-hour period was higher in the saline group than the ropivacaine group (p < 0.001). CONCLUSIONS: Parasternal blocks with ropivacaine appear to be a simple, safe, and useful technique of supplementation of postoperative analgesia in pediatric patients undergoing cardiac surgery with a median sternotomy.
RCT Entities:
OBJECTIVE: The objective of this study was to assess the effectiveness of 0.5% ropivacaine used for parasternal intercostal blocks for postoperative analgesia in pediatric patients undergoing cardiac surgery. DESIGN: A randomized, controlled, prospective, double-blind study. SETTING: A tertiary care teaching hospital. PARTICIPANTS: Thirty children scheduled for cardiac surgery with a median sternotomy. INTERVENTIONS: A 0.5% ropivacaine injection with 5 doses of 0.5 to 2.0 mL on each side in the 2nd to 6th parasternal intercostal space with a total dose of ropivacaine below 5 mg/kg or the same volume of saline before sternal wound closure. MEASUREMENTS AND MAIN RESULTS: The time to extubation was significantly lower in patients administered the parasternal blocks with ropivacaine than in the control group; the mean values were 2.66 hours and 5.31 hours, respectively (p < 0.001). The pain scores were lower in the ropivacaine group compared with the saline group; mean values were 2.20 for the ropivacaine group and 4.83 for the saline group on a scale of 10. The cumulative fentanyl dose requirement over a 24-hour period was higher in the saline group than the ropivacaine group (p < 0.001). CONCLUSIONS: Parasternal blocks with ropivacaine appear to be a simple, safe, and useful technique of supplementation of postoperative analgesia in pediatric patients undergoing cardiac surgery with a median sternotomy.
Authors: Dilek Altun; Abdullah Doğan; Ahmet Arnaz; Adnan Yüksek; Yusuf Kenan Yalçınbaş; Rıza Türköz; Sinan Aşar; Tayyar Sarıoğlu Journal: Turk Gogus Kalp Damar Cerrahisi Derg Date: 2020-04-22 Impact factor: 0.332