Literature DB >> 22173695

Three-component reactions of isocyanides, dialkyl acetylenedicarboxylates, and trans-cinnamoyl chlorides for the synthesis of highly functionalized 2-vinyl furans.

Abbas Ali Esmaeili1, Mahdieh Zangouei, Rahele Hosseinabadi, Ali Reza Fakhari.   

Abstract

In this study, we present a convenient and efficient method for the synthesis of novel, highly substituted 2-vinyl furans using a three-component reaction. The zwitterions generated from the reaction of isocyanides and dialkyl acetylenedicarboxylates are reacted with trans-cinnamoyl chlorides to produce the desired products in good yields.

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Year:  2011        PMID： 22173695     DOI： 10.1007/s11030-011-9341-2

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  8 in total

1.  Multicomponent Reactions with Isocyanides.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-09-15       Impact factor: 15.336

Review 2.  Recent advances in multicomponent reactions for diversity-oriented synthesis.

Authors:  James E Biggs-Houck; Ashkaan Younai; Jared T Shaw
Journal:  Curr Opin Chem Biol       Date:  2010-04-13       Impact factor: 8.822

Review 3.  Recent developments in isocyanide based multicomponent reactions in applied chemistry.

Authors:  Alexander Dömling
Journal:  Chem Rev       Date:  2006-01       Impact factor: 60.622

4.  Strategies for innovation in multicomponent reaction design.

Authors:  Bruce Ganem
Journal:  Acc Chem Res       Date:  2009-03-17       Impact factor: 22.384

5.  Lophotoxin: a novel neuromuscular toxin from Pacific sea whips of the genus Lophogorgia.

Authors:  W Fenical; R K Okuda; M M Bandurraga; P Culver; R S Jacobs
Journal:  Science       Date:  1981-06-26       Impact factor: 47.728

6.  Applications of multicomponent reactions to the synthesis of diverse heterocyclic scaffolds.

Authors:  James D Sunderhaus; Stephen F Martin
Journal:  Chemistry       Date:  2009       Impact factor: 5.236

7.  Pd(OAc)2-catalyzed oxidative coupling reaction of benzenes with olefins in the presence of molybdovanadophosphoric acid under atmospheric dioxygen and air.

Authors:  Masayuki Tani; Satoshi Sakaguchi; Yasutaka Ishii
Journal:  J Org Chem       Date:  2004-02-20       Impact factor: 4.354

8.  Palladium-catalyzed alkenylation of quinoline-N-oxides via C-H activation under external-oxidant-free conditions.

Authors:  Junliang Wu; Xiuling Cui; Lianmei Chen; Guojie Jiang; Yangjie Wu
Journal:  J Am Chem Soc       Date:  2009-10-07       Impact factor: 15.419
  8 in total
  2 in total

Review 1.  The status of isocyanide-based multi-component reactions in Iran (2010-2018).

Authors:  Ronak Afshari; Seyyed Emad Hooshmand; Mohammad Taghi Nazeri; Siamak Javanbakht; Ahmad Shaabani; Reza Mohammadian
Journal:  Mol Divers       Date:  2020-02-18       Impact factor: 2.943

2.  Reaction between enaminones and acetylenic esters in the presence of triphenylphosphine: a convenient synthesis of alkyl 2(1-benzyl-2,4-dioxo-2,3,4,5,6,7-hexahydro-1H-indol-3-yl)acetates.

Authors:  Farough Nasiri; Massood Bayzidi; Amin Zolali
Journal:  Mol Divers       Date:  2012-08-25       Impact factor: 2.943
  2 in total

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