Josien Riphagen-Dalhuisen1, Giedre Gefenaite, Eelko Hak. 1. University of Groningen, Department of Pharmacy, Division of Pharmacoepidemiology and Pharmacoeconomics, PO Box XB45, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. j.riphagen@umcg.nl
Abstract
OBJECTIVE: Vaccinating healthcare workers (HCWs) against influenza is one of the most important methods of decreasing influenza transmission among at-risk patients in healthcare facilities. However, despite recommendations, the rate of uptake of influenza vaccine among HCWs remains low. The objective of this meta-analysis was to determine the most important predictors of seasonal influenza vaccine acceptance among HCWs in hospitals. METHOD: A literature search of PubMed and Embase resulted in 4586 hits. Screening of the titles, abstracts and full text identified 13 studies eligible for inclusion in the meta-analysis. Based on the crude data, pooled risk ratios (Mantel-Haenszel risk ratios, mhRR) and their 95% CIs were calculated using Mantel-Haenszel analysis to estimate the associations of predictors with influenza vaccination status. RESULTS AND CONCLUSION: Knowing that the vaccine is effective (mhRR 2.22; 95% CI 1.93 to 2.54), being willing to prevent influenza transmission (mhRR 2.31; 95% CI 1.97 to 2.70), believing that influenza is highly contagious (RR 2.25; 95% CI 1.66 to 3.05), believing that influenza prevention is important (mhRR 3.63; 95% CI 2.87 to 4.59) and having a family that is usually vaccinated (RR 2.32; 95% CI 1.64 to 3.28) were statistically significantly associated with a twofold higher vaccine uptake. We therefore recommend targeting these predictors when developing new influenza vaccination implementation strategies for hospital HCWs.
OBJECTIVE: Vaccinating healthcare workers (HCWs) against influenza is one of the most important methods of decreasing influenza transmission among at-risk patients in healthcare facilities. However, despite recommendations, the rate of uptake of influenza vaccine among HCWs remains low. The objective of this meta-analysis was to determine the most important predictors of seasonal influenza vaccine acceptance among HCWs in hospitals. METHOD: A literature search of PubMed and Embase resulted in 4586 hits. Screening of the titles, abstracts and full text identified 13 studies eligible for inclusion in the meta-analysis. Based on the crude data, pooled risk ratios (Mantel-Haenszel risk ratios, mhRR) and their 95% CIs were calculated using Mantel-Haenszel analysis to estimate the associations of predictors with influenza vaccination status. RESULTS AND CONCLUSION: Knowing that the vaccine is effective (mhRR 2.22; 95% CI 1.93 to 2.54), being willing to prevent influenza transmission (mhRR 2.31; 95% CI 1.97 to 2.70), believing that influenza is highly contagious (RR 2.25; 95% CI 1.66 to 3.05), believing that influenza prevention is important (mhRR 3.63; 95% CI 2.87 to 4.59) and having a family that is usually vaccinated (RR 2.32; 95% CI 1.64 to 3.28) were statistically significantly associated with a twofold higher vaccine uptake. We therefore recommend targeting these predictors when developing new influenza vaccination implementation strategies for hospital HCWs.
Authors: Thoa Thi Minh Nguyen; Kathryn E Lafond; Tung Xuan Nguyen; Phu Dac Tran; Hang Minh Nguyen; Van Thi Cam Ha; Thu Thi Do; Nga Thu Ha; Jane F Seward; Jeffrey W McFarland Journal: Vaccine Date: 2020-01-27 Impact factor: 3.641
Authors: Vanessa Cozza; Valeria Alfonsi; Maria Cristina Rota; Valerio Paolini; Marta Luisa Ciofi degli Atti Journal: BMC Public Health Date: 2015-07-24 Impact factor: 3.295
Authors: Josien Riphagen-Dalhuisen; Joep C F Kuiphuis; Arjen R Procé; Willem Luytjes; Maarten J Postma; Eelko Hak Journal: BMC Public Health Date: 2012-12-21 Impact factor: 3.295