BACKGROUND: Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. FINDINGS AND CONCLUSION: The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.
BACKGROUND: Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. FINDINGS AND CONCLUSION: The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.
Authors: Kingsley Asiedu; Bernard Amouzou; Akshay Dhariwal; Marc Karam; Derek Lobo; Sarat Patnaik; André Meheus Journal: Bull World Health Organ Date: 2008-07 Impact factor: 9.408
Authors: Michael Marks; Ventis Vahi; Oliver Sokana; Elliot Puiahi; Alex Pavluck; Zaixing Zhang; Tenneth Dalipanda; Christian Bottomley; David C Mabey; Anthony W Solomon Journal: Am J Trop Med Hyg Date: 2014-11-24 Impact factor: 2.345