| Literature DB >> 22169570 |
C Marrec1, G Picherot, C Kandel, M Caquard.
Abstract
Kikuchi disease is a histiocytic necrotizing lymphadenitis revealed by cervical lymphadenopathy and prolonged fever. It occurs predominantly in young Asian women. The pathophysiology is unknown; the main hypothesis is an autoimmune process. Although the disease usually resolves spontaneously in a few weeks or months, it may progress to systemic lupus erythematosus. Kikuchi disease is rare in children, but it should be considered a potential diagnosis in case of polyadenopathy. We relate a case of Kikuchi-Fujimoto disease in a 13-year-old boy with sickle-cell anemia. The diagnosis, which was established after 3 weeks of hospitalization, enabled us to avoid unnecessary extensive investigations and prolonged empirical treatments that may result in unintended adverse side effects.Entities:
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Year: 2011 PMID: 22169570 DOI: 10.1016/j.arcped.2011.10.003
Source DB: PubMed Journal: Arch Pediatr ISSN: 0929-693X Impact factor: 1.180