Literature DB >> 22168806

Pharmacokinetic considerations for moderate and deep sedation.

Daniel E Becker1.   

Abstract

Moderate and deep sedation can be provided using several routes of drug administration including oral (PO), inhalation, and parental injection. The safety and efficacy of these various techniques is largely dependent on pharmacokinetic principles. This continuing education article will highlight essential principles of absorption, distribution, and elimination of commonly used sedative agents.

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Year:  2011        PMID： 22168806      PMCID： PMC3237326          DOI： 10.2344/0003-3006-58.4.166

Source DB:  PubMed          Journal:  Anesth Prog        ISSN： 0003-3006


  10 in total

Review 1.  Age-related changes in protein binding of drugs: implications for therapy.

Authors:  M K Grandison; F D Boudinot
Journal:  Clin Pharmacokinet       Date:  2000-03       Impact factor: 6.447

2.  Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs.

Authors:  M A Hughes; P S Glass; J R Jacobs
Journal:  Anesthesiology       Date:  1992-03       Impact factor: 7.892

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Authors:  J E Stambaugh; I W Wainer; J K Sanstead; D M Hemphill
Journal:  J Clin Pharmacol       Date:  1976 May-Jun       Impact factor: 3.126

4.  Pharmacokinetics and clinical effects of multidose sublingual triazolam in healthy volunteers.

Authors:  Douglass L Jackson; Peter Milgrom; Gail A Heacox; Evan D Kharasch
Journal:  J Clin Psychopharmacol       Date:  2006-02       Impact factor: 3.153

5.  Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences.

Authors:  D J Greenblatt; J S Harmatz; L L von Moltke; C E Wright; A L Durol; L M Harrel-Joseph; R I Shader
Journal:  J Pharmacol Exp Ther       Date:  2000-05       Impact factor: 4.030

6.  Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam.

Authors:  D J Greenblatt; B L Ehrenberg; J Gunderman; J M Scavone; N T Tai; J S Harmatz; R I Shader
Journal:  J Pharmacol Exp Ther       Date:  1989-07       Impact factor: 4.030

7.  Comparison of oral and intramuscular preanesthetic medication for pediatric inpatient surgery.

Authors:  S C Nicolson; E K Betts; D R Jobes; L A Christianson; J W Walters; K R Mayes; W C Korevaar
Journal:  Anesthesiology       Date:  1989-07       Impact factor: 7.892

8.  Expanded studies of the pharmacokinetics and clinical effects of multidose sublingual triazolam in healthy volunteers.

Authors:  Jacqueline E Pickrell; Kazuo Hosaka; Douglass L Jackson; Masahiro Heima; Evan Kharasch; Peter M Milgrom
Journal:  J Clin Psychopharmacol       Date:  2009-10       Impact factor: 3.153

9.  Flumazenil reversal of sublingual triazolam: a randomized controlled clinical trial.

Authors:  Kazuo Hosaka; Douglass Jackson; Jacqueline E Pickrell; Masahiro Heima; Peter Milgrom
Journal:  J Am Dent Assoc       Date:  2009-05       Impact factor: 3.634

10.  The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers.

Authors:  T D Egan; H J Lemmens; P Fiset; D J Hermann; K T Muir; D R Stanski; S L Shafer
Journal:  Anesthesiology       Date:  1993-11       Impact factor: 7.892
  10 in total
  2 in total

Review 1.  Pharmacodynamic considerations for moderate and deep sedation.

Authors:  Daniel E Becker
Journal:  Anesth Prog       Date:  2012

2.  Different Analgesic Routes of Magnesium Sulfate: Intravenous versus Pectoralis II Interfascial Plane Block for Breast Cosmetic Surgeries.

Authors:  Maha A Abo-Zeid; Sameh Ghareeb; M M Abdelhalim
Journal:  Anesth Essays Res       Date:  2019 Jul-Sep
  2 in total

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