Literature DB >> 22166752

Risk factors for overweight and diabetes mellitus in residential psychiatric patients.

Evert J Mookhoek1, Willem A de Vries, Johannes E J M Hovens, Jacobus R B J Brouwers, Anton J M Loonen.   

Abstract

OBJECTIVE: To investigate the prevalence of and risk factors for overweight and diabetes mellitus in long-stay psychiatric inpatients.
METHOD: Statistical analysis of data collected from medical, laboratory, and pharmacy files.
RESULTS: 80% of the 256 patients were suffering from schizophrenia or other psychotic disorders. The prevalence of diabetes mellitus was 15%. The prevalence of a disturbed glucose tolerance was 14%. Severe overweight (BMI > 30) was positively associated with the use of clozapine (odds ratio (OR) = 2.7; 95% confidence interval (CI): 1.31-5.75), but negatively with the diagnosis schizophrenia (OR = 0.4; 95% CI: 0.22-0.88). Diabetes mellitus was associated with severe overweight (OR = 3.5; 95% CI: 1.57-7.69). Caucasian patients were at a lower risk for diabetes mellitus (OR = 0.2; 95% CI: 0.08-0.54).
CONCLUSIONS: In residential psychiatric patients, diabetes mellitus is especially associated with overweight and non-Caucasian origin. In this survey, the use of clozapine was associated with overweight, but not directly with diabetes mellitus. Diabetes mellitus is highly prevalent, which calls for screening for diabetes mellitus at regular intervals.
Copyright © 2011 S. Karger AG, Basel.

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Year:  2011        PMID: 22166752      PMCID: PMC6444616          DOI: 10.1159/000333420

Source DB:  PubMed          Journal:  Obes Facts        ISSN: 1662-4025            Impact factor:   3.942


  3 in total

1.  Prevalence and correlates of diabetes mellitus and dyslipidaemia in a long-stay inpatient schizophrenia population in Singapore.

Authors:  Saleha Shafie; Siau Pheng Lee; Samantha Bee Cheng Ong; Peizhi Wang; Esmond Seow; Hui Lin Ong; Siow Ann Chong; Mythily Subramaniam
Journal:  Singapore Med J       Date:  2018-02-12       Impact factor: 1.858

2.  The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study.

Authors:  Yanni Wang; Lingyun Zeng; Lijuan Chen; Xin Zhou; Lijuan Huo; Tingwei Wang; Yongjie Zhou; Xiangyang Zhang
Journal:  PeerJ       Date:  2021-11-30       Impact factor: 2.984

3.  Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides.

Authors:  Yanmei Li; Ruibing Su; Shuqin Xu; Qingjun Huang; Haiyun Xu
Journal:  Neuropsychiatr Dis Treat       Date:  2017-09-27       Impact factor: 2.570

  3 in total

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