| Literature DB >> 22162168 |
Yong-Li Li1, Liang Wu, Dan-Wei Ouyang, Ping Yu, Jia-Han Xia, Yue-Xing Pan, Xian-Wen Yang, Hua-Wu Zeng, Xiang-Rong Cheng, Hui-Zi Jin, Wei-Dong Zhang.
Abstract
Two new, i.e., 1 and 2, and 69 known phenolics were isolated from the aerial parts of Abies nephrolepis. These chemical constituents included 22 lignans, 30 flavonoids, and 19 other phenols. Their structures were determined mainly by analysis of the 1D- and 2D-NMR spectroscopic data. All the 71 isolates were evaluated for their inhibitory activities against lipopolysaccharide (LPS)-induced NO production in RAW 264.7 macrophages. Compound 1 exhibited a potent effect with an IC(50) value of 13.7 μg/ml.Entities:
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Year: 2011 PMID： 22162168 DOI： 10.1002/cbdv.201000373
Source DB: PubMed Journal: Chem Biodivers ISSN： 1612-1872 Impact factor: 2.408