Literature DB >> 22161306

Oxidative stress induced by aluminum oxide nanomaterials after acute oral treatment in Wistar rats.

P V Prabhakar1, Utkarsh A Reddy, S P Singh, A Balasubramanyam, M F Rahman, S Indu Kumari, Sachin B Agawane, U S N Murty, Paramjit Grover, Mohammed Mahboob.   

Abstract

This study investigated the oxidative stress induced after acute oral treatment with 500, 1000 and 2000 mg kg⁻¹ doses of Al₂O₃ -30 and -40 nm and bulk Al₂O₃ in Wistar rats. Both the nanomaterials induced significant oxidative stress in a dose-dependent manner in comparison to the bulk. There was no significant difference between the two nanomaterials. However, the effect decreased with increase with time after treatment. The histopathological examination showed lesions only in liver with Al₂O₃ nanomaterials at 2000 mg kg⁻¹.
Copyright © 2011 John Wiley & Sons, Ltd.

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Year:  2011        PMID： 22161306     DOI： 10.1002/jat.1775

Source DB:  PubMed          Journal:  J Appl Toxicol        ISSN： 0260-437X            Impact factor:   3.446


  17 in total

Review 1.  Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts.

Authors:  Calvin C Willhite; Nataliya A Karyakina; Robert A Yokel; Nagarajkumar Yenugadhati; Thomas M Wisniewski; Ian M F Arnold; Franco Momoli; Daniel Krewski
Journal:  Crit Rev Toxicol       Date:  2014-10       Impact factor: 5.635

2.  Biomarkers of oxidative stress in rat for assessing toxicological effects of heavy metal pollution in river water.

Authors:  Utkarsh A Reddy; P V Prabhakar; G Sankara Rao; Pasham Rajasekhar Rao; K Sandeep; M F Rahman; S Indu Kumari; Paramjit Grover; Haseeb A Khan; M Mahboob
Journal:  Environ Sci Pollut Res Int       Date:  2015-05-05       Impact factor: 4.223

3.  Radio-Protective Effects of Melatonin on Subventricular Zone in Irradiated Rat: Decrease in Apoptosis and Upregulation of Nestin.

Authors:  Shafigheh Naseri; Seyed Mohammad Hossein Noori Moghahi; Tahmineh Mokhtari; Mehrdad Roghani; Ali Reza Shirazi; Fatemeh Malek; Tayebeh Rastegar
Journal:  J Mol Neurosci       Date:  2017-09-04       Impact factor: 3.444

4.  Cytotoxicity of aluminum oxide nanoparticles on Allium cepa root tip--effects of oxidative stress generation and biouptake.

Authors:  A Rajeshwari; S Kavitha; Sruthi Ann Alex; Deepak Kumar; Anita Mukherjee; Natarajan Chandrasekaran; Amitava Mukherjee
Journal:  Environ Sci Pollut Res Int       Date:  2015-03-21       Impact factor: 4.223

5.  Alterations in gut microbiota associated with a cafeteria diet and the physiological consequences in the host.

Authors:  J M Del Bas; M Guirro; N Boqué; A Cereto; R Ras; A Crescenti; A Caimari; N Canela; L Arola
Journal:  Int J Obes (Lond)       Date:  2017-11-23       Impact factor: 5.095

6.  Toxicological Impacts on Antioxidant Responses, Stress Protein, and Genotoxicity Parameters of Aluminum Oxide Nanoparticles in the Liver of Oreochromis niloticus.

Authors:  Özge Temiz; Ferit Kargın
Journal:  Biol Trace Elem Res       Date:  2021-05-21       Impact factor: 3.738

7.  Application of Aluminum Oxide Nanoparticles in Aspergillus terreus Cultivations: Evaluating the Effects on Lovastatin Production and Fungal Morphology.

Authors:  Tomasz Boruta; Marcin Bizukojc
Journal:  Biomed Res Int       Date:  2019-01-13       Impact factor: 3.411

8.  Biomarkers of oxidative stress for in vivo assessment of toxicological effects of iron oxide nanoparticles.

Authors:  Utkarsh A Reddy; P V Prabhakar; M Mahboob
Journal:  Saudi J Biol Sci       Date:  2015-09-30       Impact factor: 4.219

9.  Aluminium oxide nanoparticles compromise spatial learning and memory performance in rats.

Authors:  Imen M'rad; Mustapha Jeljeli; Naima Rihane; Pascal Hilber; Mohsen Sakly; Salem Amara
Journal:  EXCLI J       Date:  2018-02-14       Impact factor: 4.068

10.  Methanol-Extract/Fractions of Dacryodes edulis Leaves Ameliorate Hyperglycemia and Associated Oxidative Stress in Streptozotocin-Induced Diabetic Wistar Rats.

Authors:  Chimaobi J Ononamadu; Adamu J Alhassan; Aminu Ibrahim; Abdullahi A Imam; Godwin O Ihegboro; Tajudeen A Owolarafe; Mohammed S Sule
Journal:  J Evid Based Integr Med       Date:  2019 Jan-Dec
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