Literature DB >> 22159501

Potent and selective inhibition of T-cell protein tyrosine phosphatase (TCPTP) by a dinuclear copper(II) complex.

Caixia Yuan1, Miaoli Zhu, Qingming Wang, Liping Lu, Shu Xing, Xueqi Fu, Zheng Jiang, Shuo Zhang, Zongwei Li, Zhuoyu Li, Ruiting Zhu, Ling Ma, Liqing Xu.   

Abstract

A dinuclear Cu(II) complex, [Cu(2)(μ-IDA)(phen)(3)(NO(3))]NO(3)·4H(2)O (phen = 1,10-phenanthroline, H(2)IDA = iminodiacetic acid), was found to potently and selectively inhibit T-cell protein tyrosine phosphatase, and lead to the anti-proliferation and apoptosis of C6 glioma cells.

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Year:  2011        PMID: 22159501     DOI: 10.1039/c2cc16818a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Uptake and Toxicity of Copper Oxide Nanoparticles in C6 Glioma Cells.

Authors:  Arundhati Joshi; Wiebke Rastedt; Kathrin Faber; Aaron G Schultz; Felix Bulcke; Ralf Dringen
Journal:  Neurochem Res       Date:  2016-08-03       Impact factor: 3.996

2.  Cell-permeable bicyclic peptidyl inhibitors against T-cell protein tyrosine phosphatase from a combinatorial library.

Authors:  Hui Liao; Dehua Pei
Journal:  Org Biomol Chem       Date:  2017-11-22       Impact factor: 3.876

  2 in total

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