Literature DB >> 22159211

Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers.

Linlin Li1, Yum-Shing Wong, Tianfeng Chen, Cundong Fan, Wenjie Zheng.   

Abstract

A series of ruthenium complexes containing bis-benzimidazole derivatives have been synthesized and identified as able to target mitochondria and induce caspase-dependent apoptosis in cancer cells through superoxide overproduction.

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Year:  2011        PMID： 22159211     DOI： 10.1039/c1dt11950h

Source DB:  PubMed          Journal:  Dalton Trans        ISSN： 1477-9226            Impact factor:   4.390


  9 in total

1.  Characterization of the Activities of Dinuclear Thiolato-Bridged Arene Ruthenium Complexes against Toxoplasma gondii.

Authors:  Afonso P Basto; Joachim Müller; Riccardo Rubbiani; David Stibal; Federico Giannini; Georg Süss-Fink; Vreni Balmer; Andrew Hemphill; Gilles Gasser; Julien Furrer
Journal:  Antimicrob Agents Chemother       Date:  2017-08-24       Impact factor: 5.191

Review 2.  The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

Authors:  Leli Zeng; Pranav Gupta; Yanglu Chen; Enju Wang; Liangnian Ji; Hui Chao; Zhe-Sheng Chen
Journal:  Chem Soc Rev       Date:  2017-10-02       Impact factor: 54.564

3.  Ru(II)/diphenylphosphine/pyridine-6-thiolate complexes induce S-180 cell apoptosis through intrinsic mitochondrial pathway involving inhibition of Bcl-2 and p53/Bax activation.

Authors:  Wanessa Carvalho Pires; Benedicto Augusto Vieira Lima; Flávia de Castro Pereira; Aliny Pereira Lima; Francyelli Mello-Andrade; Hugo Delleon Silva; Monize Martins da Silva; Legna Colina-Vegas; Javier Ellena; Alzir A Batista; Elisângela de Paul Silveira-Lacerda
Journal:  Mol Cell Biochem       Date:  2017-08-09       Impact factor: 3.396

4.  Cobalt (III) complex exerts anti-cancer effects on T cell lymphoma through induction of cell cycle arrest and promotion of apoptosis.

Authors:  Praveen Kumar Verma; Rishi Kant Singh; Sandeep Kumar; Alok Shukla; Sanjay Kumar; Mannu Kumar Gond; Manoj Kumar Bharty; Arbind Acharya
Journal:  Daru       Date:  2022-03-16       Impact factor: 4.088

5.  Docking and in vitro molecular biology studies of p-anisidine-appended 1-hydroxy-2-acetonapthanone Schiff base lanthanum(iii) complexes.

Authors:  V Sathiyanarayanan; P Varun Prasath; P Chandra Sekhar; K Ravichandran; D Easwaramoorthy; Faruq Mohammad; Hamad A Al-Lohedan; Won Chun Oh; Suresh Sagadevan
Journal:  RSC Adv       Date:  2020-04-24       Impact factor: 4.036

6.  Mitochondria are the primary target in the induction of apoptosis by chiral ruthenium(II) polypyridyl complexes in cancer cells.

Authors:  Jin-Quan Wang; Ping-Yu Zhang; Chen Qian; Xiao-Juan Hou; Liang-Nian Ji; Hui Chao
Journal:  J Biol Inorg Chem       Date:  2013-11-28       Impact factor: 3.358

7.  In vitro and in vivo anti-proliferative evaluation of bis(4'-(4-tolyl)-2,2':6',2″-terpyridine)copper(II) complex against Ehrlich ascites carcinoma tumors.

Authors:  Dharmasivam Mahendiran; Raju Senthil Kumar; Vijayan Viswanathan; Devadasan Velmurugan; Aziz Kalilur Rahiman
Journal:  J Biol Inorg Chem       Date:  2017-09-07       Impact factor: 3.358

8.  Cytoxicity and apoptotic mechanism of ruthenium(II) amino acid complexes in sarcoma-180 tumor cells.

Authors:  Aliny Pereira Lima; Flávia Castro Pereira; Marcio Aurelio Pinheiro Almeida; Francyelli Mariana Santos Mello; Wanessa Carvalho Pires; Thallita Monteiro Pinto; Flávia Karina Delella; Sérgio Luis Felisbino; Virtudes Moreno; Alzir Azevedo Batista; Elisângela de Paula Silveira-Lacerda
Journal:  PLoS One       Date:  2014-10-17       Impact factor: 3.240

Review 9.  Applications of Ruthenium Complex in Tumor Diagnosis and Therapy.

Authors:  Ke Lin; Zi-Zhuo Zhao; Hua-Ben Bo; Xiao-Juan Hao; Jin-Quan Wang
Journal:  Front Pharmacol       Date:  2018-11-19       Impact factor: 5.810
  9 in total

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