Literature DB >> 22158749

Effects of a phosphodiesterase inhibitor (Rolipram) on the urinary excretion of 6-sulphatoxy melatonin in man.

S A Checkley1, F Winton, T Corn, C Franey, J Arendt.   

Abstract

The urinary excretion of 6-sulphatoxymelatonin (aMT6s) from 2400 to 0600 h was significantly increased following the treatment of ten normal volunteers with a phospho diesterase inhibitor (rolipram 1 mg 8 h for 24 h). The urinary excretion of the metabolite from 0600 to 1200 h was significantly reduced after treatment with rolipram.

Entities:  

Year:  1987        PMID: 22158749     DOI: 10.1177/026988118700100105

Source DB:  PubMed          Journal:  J Psychopharmacol        ISSN: 0269-8811            Impact factor:   4.153


  1 in total

1.  An alpha 2 adrenoceptor antagonist, Org 3770, enhances nocturnal melatonin secretion in man.

Authors:  E Palazidou; A Papadopoulos; A Sitsen; S Stahl; S Checkley
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

  1 in total

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