Literature DB >> 22157979

Modeling the prevalence of age-related cataract: Waterloo eye study.

Carolyn M Machan1, Patricia K Hrynchak, Elizabeth L Irving.   

Abstract

PURPOSE: To report on the prevalence of age-related (AR) cataract in an optometric clinic population including male and female subgroups.
METHODS: Retrospective patient file data reviewed for the Waterloo Eye Study database included age, sex, date of lens extraction (LE), and presence of AR cataract [nuclear sclerosis (NS), cortical cataracts (CC), posterior subcapsular (PSC) or associated LE]. Prevalence (%) was calculated for overall AR cataract, NS, CC, PSC, and bilateral LE for all Waterloo Eye Study patients. Logistic regression analysis was used to create age functions for overall AR prevalence and for significant differences in cataract types for males and females. The distribution of homogeneous and mixed cataract and mean age of first LE were determined for males and females.
RESULTS: The prevalence of all AR, NS, CC, PSC, and bilateral LE was 35.3, 28.8, 9.9, 3.6, and 14.0%, respectively. Being female was associated with an increased prevalence of CC (odds ratio = 1.54, 95% confidence interval, 1.27 to 1.88) and bilateral LE (odds ratio = 1.41, 95% confidence interval, 1.09 to 1.84). Females reached 50% prevalence earlier than men for CC (76.7 vs. 82.6 years, p 0.05) and bilateral LE (84.6 vs. 90.5 years, p 0.05). Males had an earlier age of first LE than females (70.4 vs. 73.2 years; p 0.01).
CONCLUSIONS: Logistic regression modeling indicates that being female in this optometric clinic population was associated with an increased prevalence of CC, mixed cataract, surgical intervention, and later age of first LE. These data are important for public health planning.

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Year:  2012        PMID: 22157979     DOI: 10.1097/OPX.0b013e31823ee062

Source DB:  PubMed          Journal:  Optom Vis Sci        ISSN: 1040-5488            Impact factor:   1.973


  2 in total

1.  Correlation between microRNA-34a levels and lens opacity severity in age-related cataracts.

Authors:  K-H Chien; S-J Chen; J-H Liu; H-M Chang; L-C Woung; C-M Liang; J-T Chen; T-J Lin; S-H Chiou; C-H Peng
Journal:  Eye (Lond)       Date:  2013-05-10       Impact factor: 3.775

2.  The Effect of Cataract on Color Vision Measurement with the Low-Vision Cambridge Colour Test: Providing an Adjustment Factor for Clinical Trials.

Authors:  Jasleen K Jolly; Luke Pratt; Aman K More; Jennifer Kwan; Rebecca L Jones; Robert E MacLaren; Sher Aslam
Journal:  Ophthalmol Sci       Date:  2022-04-08
  2 in total

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