Literature DB >> 22157855

New era for novel CNS drug development.

William Z Potter1.   

Abstract

Mesh：

Year:  2012        PMID： 22157855      PMCID： PMC3238073          DOI： 10.1038/npp.2011.186

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


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  5 in total

Review 1.  How to improve R&D productivity: the pharmaceutical industry's grand challenge.

Authors:  Steven M Paul; Daniel S Mytelka; Christopher T Dunwiddie; Charles C Persinger; Bernard H Munos; Stacy R Lindborg; Aaron L Schacht
Journal:  Nat Rev Drug Discov       Date:  2010-02-19       Impact factor: 84.694

2.  Can Functional Magnetic Resonance Imaging Improve Success Rates in CNS Drug Discovery?

Authors:  David Borsook; Richard Hargreaves; Lino Becerra
Journal:  Expert Opin Drug Discov       Date:  2011-06-01       Impact factor: 6.098

3.  Lack of efficacy of the substance p (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder.

Authors:  Martin Keller; Stuart Montgomery; William Ball; Mary Morrison; Duane Snavely; Guanghan Liu; Richard Hargreaves; Jarmo Hietala; Christopher Lines; Katherine Beebe; Scott Reines
Journal:  Biol Psychiatry       Date:  2005-10-24       Impact factor: 13.382

4.  Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia.

Authors:  Emmanuel Pinard; Alexander Alanine; Daniela Alberati; Markus Bender; Edilio Borroni; Patrick Bourdeaux; Virginie Brom; Serge Burner; Holger Fischer; Dominik Hainzl; Remy Halm; Nicole Hauser; Synese Jolidon; Judith Lengyel; Hans-Peter Marty; Thierry Meyer; Jean-Luc Moreau; Roland Mory; Robert Narquizian; Mathias Nettekoven; Roger D Norcross; Bernd Puellmann; Philipp Schmid; Sebastien Schmitt; Henri Stalder; Roger Wermuth; Joseph G Wettstein; Daniel Zimmerli
Journal:  J Med Chem       Date:  2010-06-24       Impact factor: 7.446

5.  Blockade of TNF-α rapidly inhibits pain responses in the central nervous system.

Authors:  Andreas Hess; Roland Axmann; Juergen Rech; Stefanie Finzel; Cornelia Heindl; Silke Kreitz; Marina Sergeeva; Marc Saake; Meritxell Garcia; George Kollias; Rainer H Straub; Olaf Sporns; Arnd Doerfler; Kay Brune; Georg Schett
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-18       Impact factor: 11.205
  5 in total
  4 in total

Review 1.  Lost but making progress--Where will new analgesic drugs come from?

Authors:  David Borsook; Richard Hargreaves; Chas Bountra; Frank Porreca
Journal:  Sci Transl Med       Date:  2014-08-13       Impact factor: 17.956

Review 2.  Emerging Insights for Translational Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Studies: Towards Prediction of Nose-to-Brain Transport in Humans.

Authors:  Mitchel J R Ruigrok; Elizabeth C M de Lange
Journal:  AAPS J       Date:  2015-02-19       Impact factor: 4.009

Review 3.  Medications for substance use disorders (SUD): emerging approaches.

Authors:  Eduardo R Butelman; Mary Jeanne Kreek
Journal:  Expert Opin Emerg Drugs       Date:  2017-10-30       Impact factor: 4.191

4.  Brain activity patterns in high-throughput electrophysiology screen predict both drug efficacies and side effects.

Authors:  Peter M Eimon; Mostafa Ghannad-Rezaie; Gianluca De Rienzo; Amin Allalou; Yuelong Wu; Mu Gao; Ambrish Roy; Jeffrey Skolnick; Mehmet Fatih Yanik
Journal:  Nat Commun       Date:  2018-01-15       Impact factor: 14.919
  4 in total

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