Literature DB >> 22156650

RE: Pattern of presentation in type 1 diabetic patients at the diabetes center of a university hospital.

Mahmood Al-Meddalawi.   

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Year:  2012        PMID: 22156650      PMCID: PMC6087638          DOI: 10.5144/0256-4947.2012.97b

Source DB:  PubMed          Journal:  Ann Saudi Med        ISSN: 0256-4947            Impact factor:   1.526


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To the Editor: The frequency of diabetic ketoacidosis (DKA) at diagnosis (49.9%) reported by Al Rashed1 is still unacceptably high compared to the usual frequency of 20% to 25%. Al Rashed1 did not address factors contributing to that high frequency. However, I presume that the following three points might be contributory: 1) The consequence of the overall increased incidence of childhood diabetes mellitus in Saudi Arabia over the past 18 years,2 2) since Al Rashed1 did not address other demographic variables in his study like parental education and socioeconomic status, I presume that these factors might influence the frequency of DKA in his population as it was found that DKA at diagnosis was associated with lower family income and lower parental education,3 and 3) though children under the age of 5 years constituted only 3.5% of the studied population in the Al Rashed study,1 increasing evidence has emerged that difficulties in diagnosing type 1 diabetes mellitus (T1DM) are a significant cause of DKA development in children with new-onset T1DM. Patient age at presentation was found to be the main risk factor for delayed diagnosis, especially in children younger than 2 years.4 Moreover, diabetic children overall had more medical encounters before diagnosis than control subjects. Children with DKA were found to be less likely to have had relevant laboratory testing before diagnosis than children with diabetes without DKA.5 Increasing public awareness and greater pediatrician alertness are solicited to decrease the high rates of DKA in new onset type 1 diabetic children.
  5 in total

1.  Incidence trends of childhood type 1 diabetes in eastern Saudi Arabia.

Authors:  Mohammad A Abduljabbar; Jamal M Aljubeh; Antony Amalraj; Mathew P Cherian
Journal:  Saudi Med J       Date:  2010-04       Impact factor: 1.484

2.  Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study.

Authors:  Arleta Rewers; Georgeanna Klingensmith; Cralen Davis; Diana B Petitti; Catherine Pihoker; Beatriz Rodriguez; I David Schwartz; Giuseppina Imperatore; Desmond Williams; Lawrence M Dolan; Dana Dabelea
Journal:  Pediatrics       Date:  2008-05       Impact factor: 7.124

3.  Is diabetic ketoacidosis at disease onset a result of missed diagnosis?

Authors:  Helen Bui; Teresa To; Robert Stein; Kinwah Fung; Denis Daneman
Journal:  J Pediatr       Date:  2009-12-03       Impact factor: 4.406

4.  Difficulties or mistakes in diagnosing type 1 diabetes in children?--demographic factors influencing delayed diagnosis.

Authors:  Małgorzata Pawłowicz; Dorota Birkholz; Maciej Niedźwiecki; Anna Balcerska
Journal:  Pediatr Diabetes       Date:  2009-05-28       Impact factor: 4.866

5.  Pattern of presentation in type 1 diabetic patients at the diabetes center of a university hospital.

Authors:  Abdulaziz M Al Rashed
Journal:  Ann Saudi Med       Date:  2011 May-Jun       Impact factor: 1.526

  5 in total

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