| Literature DB >> 2215534 |
R Vrijsen1, Y Michotte, A Boeyé.
Abstract
The mutagenicity of quercetin was reinvestigated using the Salmonella/microsome test. The mutagenicity of quercetin was enhanced by the cytosolic fraction of liver extract (S100), or by ascorbate, and even more by the complete liver supernatant (S9) in the presence of cofactors (NADP and glucose-6-phosphate). The formation of metabolites by the S9 enzymes was demonstrated by reverse-phase HPLC.Entities:
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Year: 1990 PMID： 2215534 DOI： 10.1016/0027-5107(90)90130-v
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433