Literature DB >> 22154850

Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling.

Daniel C Lim1, Brian M Cooke, Christian Doerig, Jeroen P J Saeij.   

Abstract

Some apicomplexan parasites have evolved distinct protein kinase families to modulate host cell structure and function. Toxoplasma gondii rhoptry protein kinases and pseudokinases are involved in virulence and modulation of host cell signalling. The proteome of Plasmodium falciparum contains a family of putative kinases called FIKKs, some of which are exported to the host red blood cell and might play a role in erythrocyte remodelling. In this review we will discuss kinases known to be critical for host cell invasion, intracellular growth and egress, focusing on (i) calcium-dependent protein kinases and (ii) the secreted kinases that are unique to Toxoplasma (rhoptry protein kinases and pseudokinases) and Plasmodium (FIKKs).
Copyright © 2011 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 22154850      PMCID: PMC3428259          DOI: 10.1016/j.ijpara.2011.11.007

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN: 0020-7519            Impact factor:   3.981


  102 in total

Review 1.  Linking the kinome and phosphorylome--a comprehensive review of approaches to find kinase targets.

Authors:  Richelle Sopko; Brenda J Andrews
Journal:  Mol Biosyst       Date:  2008-07-17

2.  ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity.

Authors:  Gilles Labesse; Muriel Gelin; Yannick Bessin; Maryse Lebrun; Julien Papoin; Rachel Cerdan; Stefan T Arold; Jean-François Dubremetz
Journal:  Structure       Date:  2009-01-14       Impact factor: 5.006

Review 3.  Intracellular survival of apicomplexan parasites and host cell modification.

Authors:  Carsten G K Lüder; Rebecca R Stanway; Marie Chaussepied; Gordon Langsley; Volker T Heussler
Journal:  Int J Parasitol       Date:  2008-10-25       Impact factor: 3.981

4.  The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes.

Authors:  T Melzer; A Duffy; L M Weiss; S K Halonen
Journal:  Infect Immun       Date:  2008-09-02       Impact factor: 3.441

5.  Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells.

Authors:  Björn F C Kafsack; Janethe D O Pena; Isabelle Coppens; Sandeep Ravindran; John C Boothroyd; Vern B Carruthers
Journal:  Science       Date:  2008-12-18       Impact factor: 47.728

6.  Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages.

Authors:  Yanlin Zhao; David J P Ferguson; Douglas C Wilson; Jonathan C Howard; L David Sibley; George S Yap
Journal:  J Immunol       Date:  2009-03-15       Impact factor: 5.422

Review 7.  Calcium regulation and signaling in apicomplexan parasites.

Authors:  Kisaburo Nagamune; Silvia N Moreno; Eduardo N Chini; L David Sibley
Journal:  Subcell Biochem       Date:  2008

8.  Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.

Authors:  Yang O Zhao; Aliaksandr Khaminets; Julia P Hunn; Jonathan C Howard
Journal:  PLoS Pathog       Date:  2009-02-06       Impact factor: 6.823

9.  The Apicomplexan whole-genome phylogeny: an analysis of incongruence among gene trees.

Authors:  Chih-Horng Kuo; John P Wares; Jessica C Kissinger
Journal:  Mol Biol Evol       Date:  2008-09-26       Impact factor: 16.240

10.  The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase.

Authors:  Judith L Green; Roxanne R Rees-Channer; Stephen A Howell; Stephen R Martin; Ellen Knuepfer; Helen M Taylor; Munira Grainger; Anthony A Holder
Journal:  J Biol Chem       Date:  2008-09-03       Impact factor: 5.157

View more
  31 in total

1.  Structure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence.

Authors:  Daniel Lim; Daniel A Gold; Lindsay Julien; Emily E Rosowski; Wendy Niedelman; Michael B Yaffe; Jeroen P J Saeij
Journal:  J Biol Chem       Date:  2013-10-15       Impact factor: 5.157

Review 2.  Three-dimensional structures in the design of therapeutics targeting parasitic protozoa: reflections on the past, present and future.

Authors:  Wim G J Hol
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2015-04-16       Impact factor: 1.056

Review 3.  SH3 domains: modules of protein-protein interactions.

Authors:  Natalya Kurochkina; Udayan Guha
Journal:  Biophys Rev       Date:  2012-06-20

Review 4.  Genomics of apicomplexan parasites.

Authors:  Lakshmipuram Seshadri Swapna; John Parkinson
Journal:  Crit Rev Biochem Mol Biol       Date:  2017-02-22       Impact factor: 8.250

5.  Evaluation of 4-Amino 2-Anilinoquinazolines against Plasmodium and Other Apicomplexan Parasites In Vitro and in a P. falciparum Humanized NOD-scid IL2Rγnull Mouse Model of Malaria.

Authors:  Paul R Gilson; William Nguyen; William A Poole; Jose E Teixeira; Jennifer K Thompson; Kaiyuan Guo; Rebecca J Stewart; Trent D Ashton; Karen L White; Laura M Sanz; Francisco-Javier Gamo; Susan A Charman; Sergio Wittlin; James Duffy; Christopher J Tonkin; Wai-Hong Tham; Brendan S Crabb; Brian M Cooke; Christopher D Huston; Alan F Cowman; Brad E Sleebs
Journal:  Antimicrob Agents Chemother       Date:  2019-02-26       Impact factor: 5.191

6.  Trypanosoma cruzi-secreted vesicles have acid and alkaline phosphatase activities capable of increasing parasite adhesion and infection.

Authors:  Roberta F C Neves; Anne C S Fernandes; José R Meyer-Fernandes; Thais Souto-Padrón
Journal:  Parasitol Res       Date:  2014-06-07       Impact factor: 2.289

7.  CDPKs of Cryptosporidium parvum--stage-specific expression in vitro.

Authors:  Manja Etzold; Matthias Lendner; Arwid Daugschies; Viktor Dyachenko
Journal:  Parasitol Res       Date:  2014-05-09       Impact factor: 2.289

8.  Atypical mitogen-activated protein kinase phosphatase implicated in regulating transition from pre-S-Phase asexual intraerythrocytic development of Plasmodium falciparum.

Authors:  Bharath Balu; Christopher Campbell; Jennifer Sedillo; Steven Maher; Naresh Singh; Phaedra Thomas; Min Zhang; Alena Pance; Thomas D Otto; Julian C Rayner; John H Adams
Journal:  Eukaryot Cell       Date:  2013-06-28

9.  In silico prediction of antimalarial drug target candidates.

Authors:  Philipp Ludin; Ben Woodcroft; Stuart A Ralph; Pascal Mäser
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2012-07-17       Impact factor: 4.077

10.  Contribution of introns to the species diversity associated with the apicomplexan parasite, Neospora caninum.

Authors:  Larissa Calarco; John Ellis
Journal:  Parasitol Res       Date:  2020-01-03       Impact factor: 2.289

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.