Literature DB >> 22154790

Effects of gender and ethnicity on outcomes after aortic valve replacement.

Sotiris C Stamou1, Michael Robich, Robert E Wolf, Ann Lovett, Sharon-Lise T Normand, Frank W Sellke.   

Abstract

OBJECTIVE: To evaluate the clinical outcomes after aortic valve replacement or aortic valve replacement and coronary artery bypass grafting in a large contemporary population, and to determine if outcomes are associated with patient ethnicity and gender status.
METHODS: Using the Massachusetts Cardiac Surgery Database, we identified 6809 adults aged 18 years or older who had undergone isolated aortic valve replacement or aortic valve replacement and coronary artery bypass grafting in all non-federal acute-care Massachusetts hospitals from 2002 to 2008. Univariate and multivariate logistic regression analyses were used to identify differences in patient characteristics, major morbidity, and 30-day and 1-year mortality between men (n=4043) and women (n=2766) and between whites (n=6481) and nonwhites (n=328).
RESULTS: The unadjusted 30-day mortality rate was 2.6% for the men and 3.1% for the women (P=.296) and 2.8% for whites and 3.7% for nonwhites (P=.342). In adjusted logistic regression models, the 30-day mortality was not different between the female and male patients (odds ratio, 0.88; 95% confidence interval, 0.26-3.02, P=.84) nor between the nonwhites and whites (odds ratio, 1.57; 95% confidence interval, 0.45-5.44; P=.48). The incidence of postoperative stroke was greater in women (3.0% women and 2.2% men, P=.031), and the incidence of postoperative myocardial infarction (10.9% women and 13.6% men; P=.001) and septicemia (1.2% women and 2.0% men; P=.009) was greater in men.
CONCLUSIONS: Ethnicity and gender were not associated with greater 30-day and 1-year mortality after aortic valve replacement or aortic valve replacement and coronary artery bypass grafting. Differences in postoperative outcomes were not observed between ethnic groups.
Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2011        PMID: 22154790     DOI: 10.1016/j.jtcvs.2011.11.023

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  4 in total

1.  Gender difference in ventricular response to aortic stenosis: insight from cardiovascular magnetic resonance.

Authors:  Joo Myung Lee; Sung-Ji Park; Seung-Pyo Lee; Eunah Park; Sung-A Chang; Hyung-Kwan Kim; Whal Lee; Yong-Jin Kim; Sang-Chol Lee; Seung Woo Park; Dae-Won Sohn; Yeon Hyeon Choe
Journal:  PLoS One       Date:  2015-03-26       Impact factor: 3.240

2.  Female sex is not a risk factor for post procedural mortality in coronary bypass surgery in the elderly: A secondary analysis of the GOPCABE trial.

Authors:  Gloria Faerber; Michael Zacher; Wilko Reents; Jochen Boergermann; Utz Kappert; Andreas Boening; Anno Diegeler; Torsten Doenst
Journal:  PLoS One       Date:  2017-08-30       Impact factor: 3.240

3.  Male-female differences in aortic valve and combined aortic valve/coronary surgery: a national cohort study in the Netherlands.

Authors:  M Mostafa Mokhles; Sadaf Soloukey Tbalvandany; Sabrina Siregar; Michel I M Versteegh; Luc Noyez; Bart van Putte; Alexander B A Vonk; Jolien W Roos-Hesselink; Ad J J C Bogers; Johanna J M Takkenberg
Journal:  Open Heart       Date:  2018-09-10

4.  Racial Differences in the Use of Aortic Valve Replacement for Treatment of Symptomatic Severe Aortic Valve Stenosis in the Transcatheter Aortic Valve Replacement Era.

Authors:  J Matthew Brennan; Martin B Leon; Paige Sheridan; Isabel J Boero; Qinyu Chen; Angela Lowenstern; Vinod Thourani; Sreekanth Vemulapalli; Kevin Thomas; Tracy Y Wang; Eric D Peterson
Journal:  J Am Heart Assoc       Date:  2020-08-11       Impact factor: 5.501

  4 in total

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