| Literature DB >> 22154092 |
Takashi Kawano1, Takahiko Tamura, Mayuko Hamaguchi, Tomoaki Yatabe, Koichi Yamashita, Masataka Yokoyama.
Abstract
Sugammadex, a new reversal agent for rocuronium, encapsulates the rocuronium molecule and results in rapid reversal of rocuronium-induced neuromuscular blockade. A case in which sugammadex was used to treat an anaphylactic reaction that occurred after rocuronium is presented. The binding/encapsulation of rocuronium by sugammadex may selectively eliminate the antigenic quaternary ammonium activity of circulating rocuronium, and prevent the propagation of rocuronium-induced anaphylaxis.Entities:
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Year: 2011 PMID： 22154092 DOI： 10.1016/j.jclinane.2011.04.015
Source DB: PubMed Journal: J Clin Anesth ISSN： 0952-8180 Impact factor: 9.452