Literature DB >> 22154050

EWSR1-ATF1 chimeric transcript in a myoepithelial tumor of soft tissue: a case report.

Uta Flucke1, Thomas Mentzel, Marian A Verdijk, Pieter J Slootweg, David H Creytens, Albert J H Suurmeijer, Bastiaan B J Tops.   

Abstract

Soft tissue myoepithelial tumors, a recently defined entity, include benign and malignant lesions showing a considerable morphological and immunohistochemical heterogeneity. EWSR1 rearrangements are well recognized in this tumor type, and some of the partner genes have been identified. Herein we describe a soft tissue myoepithelioma arising in the pelvis with an EWSR1-ATF1 fusion, therefore extending the spectrum of partner genes of EWSR1. In addition, this case indicates that there are overlapping genetic features of myoepithelial tumors, clear cell sarcoma, angiomatoid fibrous histiocytoma, and hyalinizing clear-cell carcinoma of the salivary gland.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 22154050     DOI: 10.1016/j.humpath.2011.08.004

Source DB:  PubMed          Journal:  Hum Pathol        ISSN: 0046-8177            Impact factor:   3.466


  26 in total

1.  Cutaneous Syncytial Myoepithelioma Is Characterized by Recurrent EWSR1-PBX3 Fusions.

Authors:  Vickie Y Jo; Cristina R Antonescu; Brendan C Dickson; David Swanson; Lei Zhang; Christopher D M Fletcher; Elizabeth G Demicco
Journal:  Am J Surg Pathol       Date:  2019-10       Impact factor: 6.394

2.  EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location.

Authors:  Yu-Chien Kao; Yun-Shao Sung; Lei Zhang; Chun-Liang Chen; Sumathi Vaiyapuri; Marc K Rosenblum; Cristina R Antonescu
Journal:  Am J Surg Pathol       Date:  2017-04       Impact factor: 6.394

Review 3.  Update on selected advances in the immunohistochemical and molecular genetic analysis of soft tissue tumors.

Authors:  Khin Thway; Andrew L Folpe
Journal:  Virchows Arch       Date:  2019-11-07       Impact factor: 4.064

4.  Rhabdoid Variant of Myoepithelial Carcinoma, with EWSR1 Rearrangement: Expanding the Spectrum of EWSR1-Rearranged Myoepithelial Tumors.

Authors:  Khin Thway; Nick Bown; Aisha Miah; Rob Turner; Cyril Fisher
Journal:  Head Neck Pathol       Date:  2014-07-04

5.  A Subset of Malignant Mesotheliomas in Young Adults Are Associated With Recurrent EWSR1/FUS-ATF1 Fusions.

Authors:  Patrice Desmeules; Philippe Joubert; Lei Zhang; Hikmat A Al-Ahmadie; Christopher D Fletcher; Efsevia Vakiani; Deborah F Delair; Natasha Rekhtman; Marc Ladanyi; William D Travis; Cristina R Antonescu
Journal:  Am J Surg Pathol       Date:  2017-07       Impact factor: 6.394

Review 6.  [Molecular pathology of soft tissue tumors: Contribution to diagnosis and therapy prediction].

Authors:  K Schmitz; H-U Schildhaus
Journal:  Pathologe       Date:  2015-03       Impact factor: 1.011

7.  Histopathological, immunohistochemical and molecular spectrum of myoepithelial tumours of soft tissues.

Authors:  Bharat Rekhi; Mukund Sable; Nirmala A Jambhekar
Journal:  Virchows Arch       Date:  2012-10-25       Impact factor: 4.064

8.  Cutaneous syncytial myoepithelioma: clinicopathologic characterization in a series of 38 cases.

Authors:  Vickie Y Jo; Cristina R Antonescu; Lei Zhang; Paola Dal Cin; Jason L Hornick; Christopher D M Fletcher
Journal:  Am J Surg Pathol       Date:  2013-05       Impact factor: 6.394

9.  Malignant round cell tumor of bone with EWSR1-NFATC2 gene fusion.

Authors:  Navid Sadri; Julieta Barroeta; Svetlana D Pack; Zied Abdullaev; Bishwanath Chatterjee; Raghunath Puthiyaveettil; John S Brooks; Frederic G Barr; Paul J Zhang
Journal:  Virchows Arch       Date:  2014-07-04       Impact factor: 4.064

10.  Soft Tissue Myoepithelial Carcinoma Metastatic to the Cecum: Highlighting an Unusual Metastatic Pattern and the Need for Diagnostic Awareness.

Authors:  Despoina Mourtzoukou; Shane Zaidi; Robin L Jones; Cyril Fisher; Khin Thway
Journal:  Rare Tumors       Date:  2016-03-31
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