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Literature DB >> 22152977

Lyngbyaureidamides A and B, two anabaenopeptins from the cultured freshwater cyanobacterium Lyngbya sp. (SAG 36.91).

Jiachen Zi¹, Daniel D Lantvit, Steven M Swanson, Jimmy Orjala.

Abstract

Two anabaenopeptin-type peptides, lyngbyaureidamides A and B, together with two previously reported peptides lyngbyazothrins C and D, were isolated from the cultured freshwater cyanobacterium Lyngbya sp. (SAG 36.91). Their structures were determined by spectroscopic and chemical methods. Lyngbyazothrins C and D were also able to inhibit the 20S proteasome with IC(50) values of 7.1 μM and 19.2 μM, respectively, while lyngbyaureidamides A and B were not active at 50 μM.

Entities: CellLine Chemical Disease Gene Species

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Year: 2011 PMID： 22152977 PMCID： PMC3262893 DOI： 10.1016/j.phytochem.2011.09.017

Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072

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