Literature DB >> 22151446

Safety and efficacy of preoperative right portal vein embolization in patients at risk for postoperative liver failure following major right hepatectomy.

Kristen P Massimino1, Kenneth J Kolbeck, C Kristian Enestvedt, Susan Orloff, Kevin G Billingsley.   

Abstract

BACKGROUND: Right portal vein embolization (RPVE) has been utilized with or without segment IV (RPVE + IV) prior to hepatectomy to induce hypertrophy and prevent liver insufficiency in patients with a predicted future liver remnant (FLR) of ≤30% or cirrhosis.
METHODS: Records of patients who underwent RPVE during 2006-2010 were retrospectively reviewed. Patient demographics, operative outcomes and complications were analysed. Computed tomography-based volumetrics were performed to determine FLR volume and degree of hypertrophy. Patients were stratified by segment IV embolization. Short-term outcomes following RPVE and liver resection are reported.
RESULTS: A total of 23 patients were identified. Ten patients underwent RPVE and 13 underwent RPVE + IV. The RPVE procedure resulted in a 38% increase in FLR volume. Liver volumes, hypertrophy rates and outcomes were similar in both groups. Rates of operative complications in the RPVE and RPVE + IV groups were similar at 50% and 54%, respectively, and most complications were minor. Complication rates as a result of embolization were 30% in the RPVE group and 31% in the RPVE + IV group. One patient underwent modified operative resection as a result of a complication of RPVE.
CONCLUSIONS: Right portal vein embolization (±segment IV) is a safe and effective modality to increase FLR volume. Post-embolization complications and short-term outcomes after resection are acceptable and are similar in both RPVE and RPVE + IV.
© 2011 International Hepato-Pancreato-Biliary Association.

Entities:  

Mesh:

Year:  2011        PMID: 22151446      PMCID: PMC3252986          DOI: 10.1111/j.1477-2574.2011.00402.x

Source DB:  PubMed          Journal:  HPB (Oxford)        ISSN: 1365-182X            Impact factor:   3.647


  22 in total

1.  Influence of preoperative chemotherapy on the risk of major hepatectomy for colorectal liver metastases.

Authors:  Mehdi Karoui; Christophe Penna; Mohamed Amin-Hashem; Emmanuel Mitry; Stephane Benoist; Brigitte Franc; Philippe Rougier; Bernard Nordlinger
Journal:  Ann Surg       Date:  2006-01       Impact factor: 12.969

2.  Extension of right portal vein embolization to segment IV portal branches.

Authors:  Lorenzo Capussotti; Andrea Muratore; Alessandro Ferrero; Giovanni Carlo Anselmetti; Andrea Corgnier; Daniele Regge
Journal:  Arch Surg       Date:  2005-11

3.  Standardized liver volumetry for portal vein embolization.

Authors:  Dario Ribero; Yun Shin Chun; Jean-Nicolas Vauthey
Journal:  Semin Intervent Radiol       Date:  2008-06       Impact factor: 1.513

4.  Body surface area and body weight predict total liver volume in Western adults.

Authors:  Jean-Nicolas Vauthey; Eddie K Abdalla; Dorota A Doherty; Philippe Gertsch; Marc J Fenstermacher; Evelyne M Loyer; Jan Lerut; Roland Materne; Xuemei Wang; Arthur Encarnacion; Delise Herron; Christian Mathey; Giovanni Ferrari; Chuslip Charnsangavej; Kim-Anh Do; Alban Denys
Journal:  Liver Transpl       Date:  2002-03       Impact factor: 5.799

5.  Preoperative percutaneous portal vein embolization: evaluation of adverse events in 188 patients.

Authors:  Donatella R Di Stefano; Thierry de Baere; Alban Denys; Antoine Hakime; Gilles Gorin; Michel Gillet; Jean Saric; Hervé Trillaud; Philippe Petit; Jean-Michel Bartoli; Dominique Elias; Jean-Robert Delpero
Journal:  Radiology       Date:  2004-12-10       Impact factor: 11.105

Review 6.  Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases.

Authors:  D Zorzi; A Laurent; T M Pawlik; G Y Lauwers; J-N Vauthey; E K Abdalla
Journal:  Br J Surg       Date:  2007-03       Impact factor: 6.939

Review 7.  Quality improvement for portal vein embolization.

Authors:  Alban Denys; Pierre Bize; Nicolas Demartines; Frederic Deschamps; Thierry De Baere
Journal:  Cardiovasc Intervent Radiol       Date:  2010-02-04       Impact factor: 2.740

8.  Three hundred and one consecutive extended right hepatectomies: evaluation of outcome based on systematic liver volumetry.

Authors:  Yoji Kishi; Eddie K Abdalla; Yun Shin Chun; Daria Zorzi; David C Madoff; Michael J Wallace; Steven A Curley; Jean-Nicolas Vauthey
Journal:  Ann Surg       Date:  2009-10       Impact factor: 12.969

9.  Postoperative liver dysfunction and future remnant liver: where is the limit? Results of a prospective study.

Authors:  Alessandro Ferrero; Luca Viganò; Roberto Polastri; Andrea Muratore; Haris Eminefendic; Daniele Regge; Lorenzo Capussotti
Journal:  World J Surg       Date:  2007-08       Impact factor: 3.352

10.  Combined portal vein embolization and neoadjuvant chemotherapy as a treatment strategy for resectable hepatic colorectal metastases.

Authors:  Anne M Covey; Karen T Brown; William R Jarnagin; Lynn A Brody; Lawrence Schwartz; Scott Tuorto; Constantinos T Sofocleous; Michael D'Angelica; George I Getrajdman; Ronald DeMatteo; Nancy E Kemeny; Yuman Fong
Journal:  Ann Surg       Date:  2008-03       Impact factor: 12.969

View more
  6 in total

1.  Identification of cofactors influencing hypertrophy of the future liver remnant after portal vein embolization-the effect of collaterals on embolized liver volume.

Authors:  Martin Zeile; Artur Bakal; Jan E Volkmer; Gregor A Stavrou; Philip Dautel; Jan Hoeltje; Axel Stang; Karl J Oldhafer; Roland Brüning
Journal:  Br J Radiol       Date:  2016-10-12       Impact factor: 3.039

2.  Volume regeneration of segments 2 and 3 after right portal vein embolization in patients undergoing two-stage hepatectomy.

Authors:  Yoshihiro Mise; Thomas A Aloia; Claudius Conrad; Steven Y Huang; Michael J Wallace; Jean-Nicolas Vauthey
Journal:  J Gastrointest Surg       Date:  2014-08-05       Impact factor: 3.452

Review 3.  Portal Vein Embolization as an Oncosurgical Strategy Prior to Major Hepatic Resection: Anatomic, Surgical, and Technical Considerations.

Authors:  Sonia T Orcutt; Katsuhiro Kobayashi; Mark Sultenfuss; Brian S Hailey; Anthony Sparks; Bighnesh Satpathy; Daniel A Anaya
Journal:  Front Surg       Date:  2016-03-11

4.  Segment 2/3 Hypertrophy is Greater When Right Portal Vein Embolisation is Extended to Segment 4 in Patients with Colorectal Liver Metastases: A Retrospective Cohort Study.

Authors:  Christopher J Hammond; Saadat Ali; Hafizul Haq; Lorna Luo; Judith I Wyatt; Giles J Toogood; J Peter A Lodge; Jai V Patel
Journal:  Cardiovasc Intervent Radiol       Date:  2019-01-17       Impact factor: 2.740

Review 5.  A Comparison of Pitfalls after ALPPS Stage 1 or Portal Vein Embolization in Small-for-Size Setting Hepatectomies.

Authors:  Andreas A Schnitzbauer
Journal:  Visc Med       Date:  2017-12-04

6.  Predictive Factors for Hypertrophy of the Future Liver Remnant After Portal Vein Embolization: A Systematic Review.

Authors:  E A Soykan; B M Aarts; M Lopez-Yurda; K F D Kuhlmann; J I Erdmann; N Kok; K P van Lienden; E A Wilthagen; R G H Beets-Tan; O M van Delden; F M Gomez; E G Klompenhouwer
Journal:  Cardiovasc Intervent Radiol       Date:  2021-06-17       Impact factor: 2.740

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.